Pediatric Patient with DIPG/DMG and Genetic Mutations

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This case study presents a 0.5-year-old patient diagnosed with Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG) with genetic mutations in H3F3A and TP53. The patient has not undergone prior treatment and is at WHO grade IV stage. Images of tissue samples and stains are provided for reference.

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Uploaded on Jul 18, 2024 | 1 Views

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  1. PBT-22FHTC Patient Age: 5 yrs Gender: nd Location: pons Diagnosis: DIPG/DMG H3.3 K27M Pre-treatment: no prior treatment Source: biopsy Stage: WHO grade IV Genetic mutations: H3F3A (p.K28M) TP53 (p.R306*)

  2. PBT-22FH H&E staining Primary Tumor

  3. PBT-22FH H3 K27M Stain Primary Tumor

  4. PBT-22FHTC Tissue Culture Laminin coated plastic

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