PASQAL: QML Progress Panagiotis Barkoutsos, VP Quantum Algorithms

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PASQAL : QML Progress
Panagiotis Barkoutsos, VP Quantum Algorithms
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PASQAL at a Glance
200
+
 
EMPLOYEES
18 nationalities
40
 
YEARS
History in quantum
technologies
15+
 
PATENTS &
APPLICATIONS
800+ publications
350+
 
QUBITS
Best-in-class qubit count
and path to 10,000 qubits
available in the cloud in
2026
>20
 
CLIENTS
Multiple QPUs sold via
HPCQS framework,
activities in more than 10
countries, and engagements
with top cloud distributors
FULL-STACK
 
QUANTUM HARDWARE
AND SOFTWARE TODAY
Aiming for Practical
Quantum Advantage
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Current
ly available 
system
s
 
are in the order of
 
300+
qubits
 
Clear blueprint to showcase  1000 qubits in near-
term
 
Analog and analog-digital capabilities
 
Development of Algorithms and Solutions
PASQAL Hardware
PASQAL manufacturers industrialized neutral-atoms type quantum processors offering attractive
scaling, flexible topology and analog and digital computational mode
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Hardware
1
Offerings
Our Full-Stack Solution is Key to Driving Customer Success
PASQAL’s comprehensive full-stack offer covers the full range of needs from the quantum
computer hardware to the way to use it on personalized software on use cases
Gen 1
100 / 200-Q
Gen 2
512 / 1,024-Q
Gen 3
5,000 / 10,000-Q
and beyond
GPU Cluster
[1] Q represents qubits
[2] CFD represents computational fluid dynamics
Emulator
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Merger PASQAL <> Qu&Co for application-driven Research
Application-driven in-house quantum algorithm research
Accelerating research and the road towards quantum advantage by
combining HW technology & problem orientations
In January 2022, PASQAL announced merging with
quantum software startup Qu&Co
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PASQAL’S Mission
We want to make the world and industry
quantum-ready
, and develop concrete 
quantum
solutions 
for their most valuable problems.
 
 
At the same time, we are eager to research
towards 
quantum advantage 
and the impact it
can have to our socio-economic world.
undefined
Where do we see quantum advantage in the near future?
Use Cases with relevance to the industry and the socio-economic world
Quantum Advantage Candidates
Current Technologies
300+ Physical Qubits are available
 
Fault Tolerance is still a regime to be explored
 
Error Mitigation Techniques
 
Some sort of advantage can be demonstrated
Classically Hard Problem
 
Relevant solution takes too much time if feasible
 
Use Case has an impact for our world
 
Have a benchmark (at least in smaller scale)
Computational Advantage will arise in the design of quantum solutions (and algorithms) for classically
hard problems and use cases with 
relevance to our world.
Accuracy and Precision should not be mixed !
We care for both (at least in most cases!)
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Application: Quantum Simulation for Scientific discovery
Analog Quantum Simulation are already operating in a regime going beyond the capabilities of classical
supercomputers
Staggered magnetisation histograms for 10 × 10
and 14 × 14 arrays, with MPS shown on the lower
part of the 10 × 10 array (14 days for simulation
with TeNPy).
undefined
Application: Learning on Graph-structured data
Graph Machine Learning
 offers a QML opportunity native to reprogrammable neutral atoms
Quantum procedures go beyond classical means.
Geometry induced by the quantum procedure cannot
be efficiently reproduced by classical means
Neutral atom arrays enable ‘native’ implementations
of graph machine learning techniques
Source: Work in Progress + 
“Quantum evolution kernel : Machine learning on graphs with programmable arrays of qubits”, Louis-Paul Henry, Slimane Thabet, Constantin Dalyac, Loïc Henriet
, Phys. Rev. A 104, 032416  (2021)
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Application: Enhancing classical graph ML with quantum features
Graph Machine Learning
 could benefit from quantum correlations
[1]
A
ggregation weights are computed using the long-
range correlations of a quantum system
Quantum Graph Feature maps encode graph into
Hilbert space and correlation matrices are observed
[1] “Extending Graph Transformers with Quantum Computed Aggregation”, Slimane Thabet, Romain Fouilland, Loic Henriet
, 
https://arxiv.org/abs/2210.10610
 (2022)
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[1] 
Solving nonlinear differential equations with differentiable quantum circuits 
https://arxiv.org/abs/2011.103955
 
 
Phys. Rev. A 103, 052416 (2021)
Compare with loss-
function constructed
from diff.equ. and
boundary conditions
Automatic
differentiation
through
backpropagation
Circuit differentiation
Update variational
parameters 
θ
 of the
quantum circuit
Variationally
update the NN
weights
up to 2
N
 basis functions
for fitting f(x) and df/dx
PINN
[1]
 with comparable
performance as DQC would need
 up-
to
 O(2
N
) nodes with 
high
 
connectivity
PINN
[1]
DQC
[2]
Input
Hidden layers
Output
quantum feature
map circuit
variational
quantum circuit
measure
Application: Solving Non-Linear Partial Differential Equations
DQC is a variational approach, where parametric
functions are represented by measurements on the
output of quantum circuits
The upper part describes the structure of a classical
neural network, while the lower part describes the
structure of DQC
The neural network is essentially a non-linear function
generator which, given an input x, produces an output
f(x). One trains the NN to represent the function that
solves a DE given boundary conditions. At a given step,
a loss function is evaluated and an update of the NN
weights is decided in order to improve the quality of
the output. One very important ingredient here is
automatic differentiation, which allows you to not only
have access to f, but also to the derivative of f with
respect to x
What we proposed for DQC is to use a quantum circuit
to produce a universal function generator, similar to
the classical case, sometimes also called a Quantum
Neural Network or Quantum Model
The analogue of the NN consists of a quantum circuit.
Very much like automatic differentiation for classical
neural networks, there are ways to access function
derivatives through analytical circuit differentiation
DQC
undefined
Digital / Analog setups provide a promising solution for DQC implementation
Digital
: algorithm implemented through sequence of
discrete
 quantum gate operations
 
 
Analog
: user has control over small number of
parameters and the quantum computer evolves
towards an answer 
continuously
[2]
 
 
Digital is 
universal
, but noise limits the use to 
very
short gate sequences
, which limits the near-term
potential for quantum advantage
 
 
Analog is perhaps 
not fully universal
, but
researchers are finding that it requires typically 
10
4
-
10
5
 less quantum operations
 
 
Analog quantum (or analog-digital) may therefore
very well be our best chance 
to implement DQC
workflows
Digital / Analog Quantum Computation
undefined
Application: Quantum (Scientific) Machine Learning (QSciML)
QML with Digital-Analog QNN circuits for simulating systems governed by Differential Equations
Differential Constraints Help Train Generative models
Solving known deterministic equations (PDE)
Learning DE-models based on real-world data
Optimizing control/model parameters to maximize
solution characteristics of merit
[1] 
Solving nonlinear differential equations with differentiable quantum circuits 
https://arxiv.org/abs/2011.103955
 
 
Phys. Rev. A 103, 052416 (2021)
[2] 
Protocols for Trainable and Differentiable Quantum Generative Modelling 
https://arxiv.org/abs/2202.08253
[3] 
Quantum Extremal Learning 
https://arxiv.org/abs/2205.02807
[4] 
Quantum Model Discovery 
https://arxiv.org/abs/2111.063766
undefined
From Analog applications to Digital-Analog paradigms
Pulse-level Control Paradigms
Digital-Analog
Analog
With “Analog” quantum computing, we mean continuous
control of our system Hamiltonian by the application of
optical addressing with laser light
As an example, we can operate our quantum optical
system  in the Ising model regime, where the parametric
Hamiltonian can be described as
 
 
 
 
 
 
 
In a “digital-analog” paradigm, we  define it as digital
operations, such as arbitrary single-qubit
gate(s)/rotations,  interleaved with global multi-qubit
operations such as evolution over an Ising Hamiltonian.
 
This allows efficient entanglement at low circuit depth,
while simultaneously allowing more specific control of
individual rotations
 
 
 
undefined
Where to go next in QML? What challenges are to be tackled?
Pulse-level Control Paradigms
Quantum Advantage of Quantum Neural Networks
over classical (Deep) Neural Networks?
(Analog) circuit differentiation is too expensive!
How can we do practical gradient descent?
We, as part of a broader community on the topic, have
also developed extensions of the parameter shift rule
towards more general unitaries including analog blocks
 
Recent work has expanded further on these, including
explicity formulations for analog evolutions.
 
However, for optimization based on gradient descent,
the cost compared to backpropagation is simply too
high to  be practical
 
Open questions
Can we train classically?
Can we train more cheaply?
 Stochastic?
Several papers which use expressivity arguments to
claim a theoretic advantage over classical
 
Classical neural networks were only very recently
understood more rigorously theoretically – is it simply
too early to expect the same here? Do we need a
quantum computer to understand a quantum
computer?
 
Several papers pointing out limitations of QNN and
QML in general
, but often it is not clear how broadly
applicable the statements are, and no clear solutions
exist yet
[1] 
Generalized quantum circuit differentiation rules 
https://arxiv.org/abs/2108.01218
 
Phys. Rev. A 104, 052417 (2021)
undefined
Thank you!
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Discover the latest progress of PASQAL Quantum as Panagiotis Barkoutsos, VP Quantum Algorithms, presents the advancements in quantum technologies. This confidential update highlights the company's achievements in qubit count, global engagements, and their full-stack solution.

  • PASQAL
  • QML
  • progress
  • Panagiotis Barkoutsos
  • VP Quantum Algorithms
  • quantum technologies
  • qubit count
  • full-stack solution

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  1. PASQAL : QML Progress Panagiotis Barkoutsos, VP Quantum Algorithms QTML November 2023 1 Strictly private and confidential. Not for distribution.

  2. PASQAL at a Glance >20 >20 40 40 350+ 350+ CLIENTS YEARS QUBITS Multiple QPUs sold via HPCQS framework, activities in more than 10 countries, and engagements with top cloud distributors History in quantum technologies Best-in-class qubit count and path to 10,000 qubits available in the cloud in 2026 200+ + 200 15+ 15+ FULL FULL- -STACK STACK EMPLOYEES 18 nationalities PATENTS & APPLICATIONS 800+ publications QUANTUM HARDWARE AND SOFTWARE TODAY Aiming for Practical Quantum Advantage 2 Strictly private and confidential. Not for distribution.

  3. PASQAL Hardware PASQAL manufacturers industrialized neutral scaling, flexible topology and analog and digital computational mode PASQAL manufacturers industrialized neutral- -atoms type quantum processors offering attractive scaling, flexible topology and analog and digital computational mode atoms type quantum processors offering attractive laser camera 2D acousto-optic laser beam reflector vacuum chamber dichroic mirror Currentlyavailable systemsare in the order of 300+ qubits optical clamp Hardware control electronics Clear blueprint to showcase 1000 qubits in near- term Analog and analog-digital capabilities Development of Algorithms and Solutions 3

  4. Our Full-Stack Solution is Key to Driving Customer Success PASQAL s comprehensive full-stack offer covers the full range of needs from the quantum computer hardware to the way to use it on personalized software on use cases Hardware Hardware1 1 Offerings Offerings Cloud access Data center install On-premise install Access Access Gen 1 Gen 2 Coding platform GUI Software integrations 100 / 200-Q 512 / 1,024-Q Platform Turnkey solutions per problem and sector Chemistry, CFD2, Finance Solutions Gen 3 5,000 / 10,000-Q and beyond Quantum (ready) algorithms per mathematical problem PDE, optimization, ML Libraries R&D support Tech support Maintenance GPU Cluster GPU Cluster Emulator Support [1] Q represents qubits [2] CFD represents computational fluid dynamics 4 Strictly private and confidential. Not for distribution.

  5. Merger PASQAL <> Qu&Co for application-driven Research Application-driven in-house quantum algorithm research In January 2022, PASQAL announced merging with quantum software startup Qu&Co Accelerating research and the road towards quantum advantage by combining HW technology & problem orientations Hardware Software 1-2 years earlier Technology- driven Problem- oriented 5 Strictly private and confidential. Not for distribution.

  6. PASQALS Mission We want to make the world and industry quantum solutions quantum- -ready solutions for their most valuable problems. ready, and develop concrete quantum quantum At the same time, we are eager to research towards quantum advantage can have to our socio-economic world. quantum advantage and the impact it 6 Strictly private and confidential. Not for distribution.

  7. Where do we see quantum advantage in the near future? Computational Advantage will arise in the design of quantum solutions (and algorithms) for classically hard problems and use cases with relevance to our world. Use Cases with relevance to the industry and the socio-economic world Quantum Advantage Candidates Current Technologies 300+ Physical Qubits are available Classically Hard Problem Fault Tolerance is still a regime to be explored Relevant solution takes too much time if feasible Error Mitigation Techniques Use Case has an impact for our world Some sort of advantage can be demonstrated Have a benchmark (at least in smaller scale) Accuracy and Precision should not be mixed ! Accuracy and Precision should not be mixed ! We care for both (at least in most cases!) 7 Strictly private and confidential. Not for distribution.

  8. Application: Quantum Simulation for Scientific discovery Analog Quantum Simulation are already operating in a regime going beyond the capabilities of classical supercomputers Staggered magnetisation histograms for 10 10 and 14 14 arrays, with MPS shown on the lower part of the 10 10 array (14 days for simulation with TeNPy). 8 Strictly private and confidential. Not for distribution.

  9. Application: Learning on Graph-structured data Graph Machine Learning offers a QML opportunity native to reprogrammable neutral atoms Quantum procedures go beyond classical means. Geometry induced by the quantum procedure cannot be efficiently reproduced by classical means Neutral atom arrays enable native implementations of graph machine learning techniques 0.300 0.175 0.250 0.150 0.200 0.125 Probability Probability 0.100 0.150 0.075 0.100 0.050 0.050 0.025 0.000 0.000 -15-10-5 0 5 10 15 20 Energy value -15-10-5 0 5 10 15 20 Energy value 9 Strictly private and confidential. Not for distribution. Source: Work in Progress + Quantum evolution kernel : Machine learning on graphs with programmable arrays of qubits , Louis-Paul Henry, Slimane Thabet, Constantin Dalyac, Lo c Henriet, Phys. Rev. A 104, 032416 (2021)

  10. Application: Enhancing classical graph ML with quantum features Graph Machine Learning could benefit from quantum correlations[1] Aggregation weights are computed using the long- range correlations of a quantum system Quantum Graph Feature maps encode graph into Hilbert space and correlation matrices are observed 10 Strictly private and confidential. Not for distribution. [1] Extending Graph Transformers with Quantum Computed Aggregation , Slimane Thabet, Romain Fouilland, Loic Henriet, https://arxiv.org/abs/2210.10610 (2022)

  11. Application: Solving Non-Linear Partial Differential Equations DQC DQC is a variational approach, where parametric functions are represented by measurements on the output of quantum circuits The upper part describes the structure of a classical neural network, while the lower part describes the structure of DQC The neural network is essentially a non-linear function generator which, given an input x, produces an output f(x). One trains the NN to represent the function that solves a DE given boundary conditions. At a given step, a loss function is evaluated and an update of the NN weights is decided in order to improve the quality of the output. One very important ingredient here is automatic differentiation, which allows you to not only have access to f, but also to the derivative of f with respect to x What we proposed for DQC is to use a quantum circuit to produce a universal function generator, similar to the classical case, sometimes also called a Quantum Neural Network or Quantum Model The analogue of the NN consists of a quantum circuit. Very much like automatic differentiation for classical neural networks, there are ways to access function derivatives through analytical circuit differentiation PINN[1] Variationally update the NN weights Automatic differentiation through backpropagation ? ?(?) Hidden layers Output Input Compare with loss- function constructed from diff.equ. and boundary conditions PINN[1]with comparable performance as DQC would need up- to O(2N) nodes with high connectivity ? ?? ?? ?(?) ?? ??= ?2+ sin ? + ? up to 2Nbasis functions for fitting f(x) and df/dx ? 0 = 5 Circuit differentiation | 0 | 0 | 0 | 0 ?? ? ?? (Xi) = Update variational parameters of the quantum circuit | 0 | 0 DQC[2] measure ?(??) = ??? ??(?? ) quantum feature map circuit variational quantum circuit 11 Strictly private and confidential. Not for distribution. [1] Solving nonlinear differential equations with differentiable quantum circuits https://arxiv.org/abs/2011.103955 Phys. Rev. A 103, 052416 (2021)

  12. Digital / Analog setups provide a promising solution for DQC implementation Digital / Analog Quantum Computation Digital discrete Digital: algorithm implemented through sequence of discretequantum gate operations Digital entanglers Analog parameters and the quantum computer evolves towards an answer continuously Analog: user has control over small number of Original (fully digital) DQC circuit continuously[2] Digital is universal short gate sequences potential for quantum advantage universal, but noise limits the use to very short gate sequences, which limits the near-term very Quantum feature map Digital variat, gates Digital variational gates Measurement Optimized (analog-digital) DQC circuit Analog is perhaps not fully universal researchers are finding that it requires typically 10 10 not fully universal, but 104 4- - 105 5less quantum operations less quantum operations Analog entanglers Analog quantum (or analog-digital) may therefore very well be our best chance to implement DQC workflows to implement DQC workflows 12 Strictly private and confidential. Not for distribution.

  13. Application: Quantum (Scientific) Machine Learning (QSciML) QML with Digital-Analog QNN circuits for simulating systems governed by Differential Equations Solving known deterministic equations (PDE) Differential Constraints Help Train Generative models Optimizing control/model parameters to maximize solution characteristics of merit Learning DE-models based on real-world data [1] Solving nonlinear differential equations with differentiable quantum circuits https://arxiv.org/abs/2011.103955 Phys. Rev. A 103, 052416 (2021) [2] Protocols for Trainable and Differentiable Quantum Generative Modelling https://arxiv.org/abs/2202.08253 [3] Quantum Extremal Learning https://arxiv.org/abs/2205.02807 [4] Quantum Model Discovery https://arxiv.org/abs/2111.063766 13 Strictly private and confidential. Not for distribution.

  14. From Analog applications to Digital-Analog paradigms Pulse-level Control Paradigms Digital-Analog Analog With Analog quantum computing, we mean continuous control of our system Hamiltonian by the application of optical addressing with laser light As an example, we can operate our quantum optical system in the Ising model regime, where the parametric Hamiltonian can be described as In a digital-analog paradigm, we define it as digital operations, such as arbitrary single-qubit gate(s)/rotations, interleaved with global multi-qubit operations such as evolution over an Ising Hamiltonian. This allows efficient entanglement at low circuit depth, while simultaneously allowing more specific control of individual rotations 14 Strictly private and confidential. Not for distribution.

  15. Where to go next in QML? What challenges are to be tackled? Pulse-level Control Paradigms Quantum Advantage of Quantum Neural Networks over classical (Deep) Neural Networks? (Analog) circuit differentiation is too expensive! How can we do practical gradient descent? We, as part of a broader community on the topic, have also developed extensions of the parameter shift rule towards more general unitaries including analog blocks Several papers which use expressivity arguments to claim a theoretic advantage over classical Classical neural networks were only very recently understood more rigorously theoretically is it simply too early to expect the same here? Do we need a quantum computer to understand a quantum computer? Recent work has expanded further on these, including explicity formulations for analog evolutions. However, for optimization based on gradient descent, the cost compared to backpropagation is simply too high to be practical Several papers pointing out limitations of QNN and QML in general, but often it is not clear how broadly applicable the statements are, and no clear solutions exist yet Open questions Can we train classically? Can we train more cheaply? Stochastic? 15 Strictly private and confidential. Not for distribution. [1] Generalized quantum circuit differentiation rules https://arxiv.org/abs/2108.01218 Phys. Rev. A 104, 052417 (2021)

  16. Thank you! We are hiring in a variety of seniority levels: panagiotis.barkoutsos@pasqal.com 16 Strictly private and confidential. Not for distribution.

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