Labial Fusion: Causes, Symptoms, and Treatment

 
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Introduction
 
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It is also known as 
labial fusion, labial
adhesion, labial agglutination, labial
adherence, gynatresia, vulvar fusion.
 
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It is most common in infants between 3
months to 3 years with its peak
incidence between 13-23.No cases of
neonates have 
been found so far.
 
Aetiology
 
There is no specific cause for labial
fusion though it is suggested that low
levels of oestrogen and irritative
conditions play a 
major role.
 
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Hypoestrogenemia
Recurrent or chronic local vaginal
irritation
Labial tissue trauma
Dermatological disorders
Sexual abuse
 
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It is mostly asymptomatic and can be discovered by a
parent or during routine medical examination.
Depending on severity of fusion, some patients may
have urine pooling in the vagina post urination, then
experience
subsequent urine leakage from the vagina when they
stand after voiding (post void dribbling, also called
vaginal 
voiding).
 
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Hymenal skin tags
Imperforate hymen
Paraurethral cyst
Urethral polyp
Vaginal atresia
 
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Treatment is not usually necessary in
asymptomatic cases, since most fusions will
separate naturally over time.
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A small blob of the cream or ointment is applied
daily on to the central line of fusion of the inner
lips of the vulva for 4 to 6 weeks until the
membrane starts to dissolve and the labia
eventually separates completely.
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Failure of topical Oestrogen
Strong fusion of the labia
Association with urine outflow obstruction
Association with urine retention.
 
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Recurrent 
urinary tract infection
V
ulvar vestibulitis and inflammation caused
by chronic urine exposure.
 
Anuria
 
Urinary retention
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Labial fusion is a medical condition where the labia minora partially or fully fuse together. It is most common in infants and young children, with suggested causes being low estrogen levels and irritative conditions. While often asymptomatic, some cases may lead to urinary issues. Treatment may involve natural separation over time, the use of estrogen cream, or surgical release in severe instances.

  • Labial Fusion
  • Medical Condition
  • Symptoms
  • Treatment
  • Infants
  • Estrogen Levels

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  1. LABIAL FUSION

  2. Introduction Labial fusion is a medical condition characterized by partial or complete midline fusion of labia minora. It is also known as labial fusion, labial adhesion, labial agglutination, labial adherence, gynatresia, vulvar fusion.

  3. Epidemiology It is most common in infants between 3 months to 3 years with its peak incidence between 13-23.No cases of neonates have been found so far.

  4. Aetiology There is no specific cause for labial fusion though it is suggested that low levels of oestrogen and irritative conditions play a major role.

  5. Risk Factors Hypoestrogenemia Recurrent or chronic local vaginal irritation Labial tissue trauma Dermatological disorders Sexual abuse

  6. Clinical presentation It is mostly asymptomatic and can be discovered by a parent or during routine medical examination. Depending on severity of fusion, some patients may have urine pooling in the vagina post urination, then experience subsequent urine leakage from the vagina when they stand after voiding (post void dribbling, also called vaginal voiding).

  7. Differentials Hymenal skin tags Imperforate hymen Paraurethral cyst Urethral polyp Vaginal atresia

  8. Treatment Treatment is not usually necessary in asymptomatic cases, since most fusions will separate naturally over time. Oestrogen cream A small blob of the cream or ointment is applied daily on to the central line of fusion of the inner lips of the vulva for 4 to 6 weeks until the membrane starts to dissolve and the labia eventually separates completely. Surgical release

  9. Indications Failure of topical Oestrogen Strong fusion of the labia Association with urine outflow obstruction Association with urine retention.

  10. Complications Recurrent urinary tract infection Vulvar vestibulitis and inflammation caused by chronic urine exposure. Anuria Urinary retention

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