Impact of COVID-19 on Older Adults: Vulnerabilities and Management

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Older adults face higher risks from COVID-19, with individuals aged 65+ and 85+ suffering the most severe outcomes. Vulnerabilities in aging immune systems and unique transmission characteristics contribute to the pandemic's spread. Recognizing clinical symptoms and signs early is crucial for managing cases effectively, focusing on primary prevention and supportive care to align with patient/family goals.


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  1. COVID-19 and Vulnerable Populations, Part 1: The effects on older adults Mindy J. Fain, MD Gregory K. Mayer, MD, MBA June 4, 2020

  2. COVID-19 and Older Adults: An Overview ASU College of Health Solutions June 4, 2020 Mindy J. Fain, MD Co-Director, UArizona Center on Aging

  3. Older Adults are at High Risk for COVID-19 People 65+ suffer 80% of deaths People 85+ suffer most severe outcomes Over 35% of deaths occur in nursing home patients & staff Minority groups affected disproportionately

  4. Vulnerable Older Adult: Aging Immune System Age impacts the innate and adaptive immune systems Poor outcomes if stuck in innate Progression to adaptive and antibody production associated with better outcomes Implications for vaccine strategies

  5. More About Older Adults & Vulnerability Aging physiology Chronic conditions Cognitive impairments Functional decline Frailty Congregate living Unique social determinants of health

  6. How the Unique Transmission of COVID-19 Contributes to the Pandemic Spread by person-to-person and concern for indirect contact Long, silent incubation period (2-27 days), median 5-6 days >50% of asymptomatic people shed the virus Predilection for lower respiratory tract

  7. Clinical Symptoms and Signs Older frail patients often have atypical presentations Blunted or no fever Unexplained hypoxia Tachycardia, tachypnea Delirium Fatigue, functional decline or falls Consider COVID-19 in any older adult with new-onset fever or respiratory symptoms (e.g., dry cough), or atypical complaints

  8. Management Approaches Primary prevention is most important Halt spread from infected persons High suspicion/low threshold - diagnosis and triage to appropriate level Supportive care with close monitoring for late progression (hypoxia, respiratory distress) Care aligned with patient/family goals

  9. Public Ageism and COVID-19 Public Discussion of Allocation of Scarce Resources w/age criteria Public Ageism: At least only old people are dying Public Guilt: responsible for widespread economic collapse Sudden Dependency: withdrawal of supports Sudden Exposure of Technological Gaps: telehealth, online activities False impression that most older adults live in nursing homes (only 4.5%)

  10. It Takes a Village: We Are All Interdependent

  11. References Nikolich-Zugich J, et. al.SARS-CoV-2 and COVID-19 in older adults. GeroScience (2020) 42:505-514 doi.org/10.1007/s11357-020-00186-0 Applegate W, Ouslander J. COVID-19 Presents High Risk to Older Persons. JAGS 68:681, 2020 doi: 10.1111/jgs.16426 Nanda A, et. al. COVID-19 In Older Adults. Aging Clinical and Experimental Research (2020) doi.org/10.1007/s40520-020-01581-5 Richardson S, et. al. Presenting Characteristics, Comorbidities and Outcomes Among 5700 Patients Hospitalized with COVID-19 in the NYC Area. JAMA (2020) doiI:10.1001/jama.2020.6775

  12. Thank you!

  13. Q+A

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