Evidence-Based Strategies for Treatment Adherence Improvement

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An Evidence Based Approach to
Improving Treatment Adherence
Dr. John Mahan, MD, Addiction Psychiatrist
Rhonda Spath, CADC
 
Jackson County Mental Health
 
Neither John Mahan, MD nor Rhonda
Spath have any relevant financial
disclosures to make
 
No non-FDA approved uses for
medications will be discussed
 
Gain familiarity with the behavioral principles underpinning
Contingency Management
 
Learn about voucher-based vs. prize-based reinforcement
paradigms, understand how an escalating schedule of
reinforcement can be applied to either, and appreciate that
these interventions do not cause or destabilize Gambling
Disorder.
 
Introduce how one ACT Team has implemented
Contingency Management to reinforce desired pro-recovery
behaviors, including A&D group attendance, meeting with
medical providers, and presenting for long-acting injectable
medication administration.
 
 
How to encourage clients to meet with
clinicians, adhere to medications, or
abstain from methamphetamine?
 
Benefits:
Better Physical and Mental Health
Improved Relationships
Social Productivity
 
 
 
 
To clients, the benefits of treatment plan
adherence can be long-term, and therefore
less immediate, than other competing
factors
 
Benefits:
Better Physical and Mental Health
Improved Relationships
Social Productivity
 
 
In service of Long Term
Benefit
 
Meeting with clinicians
 
 
Medication adherence
 
 
Abstinence from
methamphetamine,
cannabis, or other
substances
 
Competing Forces
 
 
Negative symptoms,
disruptive to daily life
 
Avoiding side effects, a
nuisance to remember
 
Cravings, Avoidance of
withdrawal, Desired
alteration in perception of
symptoms or difficult life
circumstances
 
A way to bring positive consequences for
treatment adherence forward in time and
to make them:
More immediate
More salient
More predictable
 
Based on Operant Behavioral Principles,
also known as Instrumental Learning or
Operant Conditioning
 
If I do 
this
, then 
that
 happens
 
OPERANT CONDITIONING
 
CLASSICAL CONDITIONING
 
Stimuli that are present when
a behavior is rewarded (or
punished) affect the
likelihood of the behavior in
the future – a thought process
 
e.g., Getting to the ACT
meeting early because you
know there will be donuts
and the best ones go fast!
 
Stimuli that signal significant
events produce 
reflexive
behavior -  often outside
conscious awareness
 
e.g., Salivating at the sight
of your favorite treat!
 
A chance at free
cannabis entices
someone to enter a
cannabis dispensary.
 
Winning free cannabis
makes it more likely an
ACT client will return
for another chance to
win free cannabis
 
Contingency
Management uses
immediate positive
reinforcers to improve
adherence to treatment
plan elements that
might otherwise have
mostly long-term
benefits.
 
Target a behavior that you can reinforce in
real time (not a delayed reward)
Attending an appointment with a
clinician
Attending a group
Successfully providing a laboratory
sample (regardless of result)
Appropriate Urine Drug Screen (point of
care is best for immediacy of results)
 
The reinforcers have to be valuable to the
participants (but they don’t have to be
expensive). Ask participants what they want!
 
Adolescents often don’t want CDs, for
example
I’d rather give health food, but participants
often desire less nutritious snacks
Can allow participants to “bank” points for
larger items they would like
 
“VOUCHER-BASED”
 
“PRIZE-BASED”
 
“VOUCHER-BASED”
 
“PRIZE-BASED”
 
Reinforcement is always the
same, no chance involved
 
Half the prizes are verbal
encouragement, some are
worth a little, a few are
worth a bit more, and one
can be pretty nice
Works equally well as a
fixed paradigm, and 
is
cheaper to run
Does NOT contribute to
development or/ relapse to
Gambling Disorder
FUN!
 
An Escalating Schedule can be applied to
either Fixed or Intermittent
reinforcement structures to improve
efficacy (escalating works better!)
 
Number of reinforcers increases with
each successive successful behavior (up
to a maximum), until participant misses
an opportunity to display the desired
behavior
 
CONSTANT
 
ESCALATING
 
First: 1
Misses one: 0
First: 1
Second in a row: 1
Misses one: 0
First: 1
Second in a row: 1
Third in a row: 1
Fourth in a row: 1
Fifth in a row: 1
Sixth in a row: 1
Seventh in a row: 1
 
First: 1
Misses one: 0
First: 1
Second in a row: 2
Misses one: 0
First: 1
Second in a row: 2
Third in a row: 3
Fourth in a row: 4
Fifth in a row: 5
Sixth in a row: 5
Seventh in a row: 5
 
Continue to reinforce the behavior with
contingency management 
at least until
the long-term benefit of the behavior
has been realized
, and perhaps longer.
 
 
This might be a long time, but why not? If
it was worth it to start, continuing is worth
it
 
Instead of stopping a reinforcer that is
working, add a new behavioral target to a
successful program for a given
participant
 
Sell it to your administrators by showing
how the cost of the program could be offset
by a decrease in lost productivity:
Missed appointments with your
psychiatrist or other internal medical
providers
Low productivity due to missed groups or
sessions with other providers
 
Decide fixed vs intermittent (cheaper)
Decide constant vs escalating (better)
Decide how many will participate
Decide how many target behaviors per
participant
How many chances per month for a
participant to demonstrate a target
behavior for a reinforcement?
Calculate (average) value of
reinforcement
 
Initial Monthly Budget
 
= Participants x Monthly Opportunities to
show target behavior x Value
 
E.g., 20 ACT clients can earn a $1 by meeting
with their Psychiatrist twice a month,
attending a weekly A&D group, or coming for
their monthly long-acting injectable
medication nurse appointment
 
=20 x (2+4+1) x $1 = $140
 
Initial Monthly Budget
 
= Participants x Monthly Opportunities to show target
behavior x Value x 
highest
 consistency multiplier
 
E.g., 20 ACT clients can earn a $1 by meeting with their
Psychiatrist twice a month, attending a weekly A&D
group, or coming for their monthly long-acting
injectable medication nurse appointment. They can
earn up to 5 $1 bills if they attend five or more in a row.
 
=20 x (2+4+1) x $1 x 5 = $700
 
Initial Monthly Budget
 
= Participants x Monthly Opportunities to show target
behavior x 
Average
 Prize Value
 
E.g., 20 ACT clients can earn a prize by meeting with
their Psychiatrist twice a month, attending a weekly
A&D group, or coming for their monthly long-acting
injectable medication nurse appointment. The Average
Prize value is $0.50
 
=20 x (2+4+1) x $0.50 = $70
 
Divide the total value of
all possible prizes by
the total number of
chances to win a prize.
 
Ignore the “free spin” slots
 
16 terminal slots
8 are free
5 are worth 100 points
2 are worth 200 points
1 is worth 500 points
 
(0+500+400+500)/16
 
=$0.87 average if 100
points is a dollar
 
Ignore the “free spin” slots
 
Initial Monthly Budget
 
= Participants x Monthly Opportunities to show target behavior x
highest
 consistency multiplier x 
Average
 Prize Value
 
E.g., 20 ACT clients can earn a prize by meeting with their
Psychiatrist twice a month, attending a weekly A&D group, or coming
for their monthly long-acting injectable medication nurse
appointment. They can earn up to 5 spins if they attend five or more
in a row.  The Average Prize value is $0.50.
 
=20 x (2+4+1) x 5 x $0.50 = $350
 
These calculations have given us an idea of
where to start with an initial budget, but
operating costs will be much lower (unless
everyone is perfect all the time!)
 
Use actual expenditures over the first
several months to make future budgets.
 
If you have more funding than you are
spending, add more behavioral targets or
improve value of prizes.
 
Medium sized ACT Team
 
Methamphetamine, Cannabis, and Alcohol
Use complicate response to treatment
 
Tobacco-related illness will cause the death
of most consumers of specialty mental
health services
 
We wanted to increase engagement in
treatment
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Explore evidence-based approaches like Contingency Management to boost treatment adherence in clients dealing with addiction. Learn methods to encourage meeting with clinicians, medication adherence, and abstaining from substances like methamphetamine. Emphasizing long-term benefits, the strategies aim to enhance physical and mental health, improve relationships, and boost social productivity. By aligning positive consequences with treatment adherence, clients can experience more immediate, salient, and predictable rewards, fostering lasting engagement in their recovery journey.

  • Evidence-Based
  • Treatment Adherence
  • Addiction Recovery
  • Contingency Management
  • Behavioral Interventions

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  1. An Evidence Based Approach to Improving Treatment Adherence Dr. John Mahan, MD, Addiction Psychiatrist Rhonda Spath, CADC Jackson County Mental Health

  2. Neither John Mahan, MD nor Rhonda Spath have any relevant financial disclosures to make No non-FDA approved uses for medications will be discussed

  3. Gain familiarity with the behavioral principles underpinning Contingency Management Learn about voucher-based vs. prize-based reinforcement paradigms, understand how an escalating schedule of reinforcement can be applied to either, and appreciate that these interventions do not cause or destabilize Gambling Disorder. Introduce how one ACT Team has implemented Contingency Management to reinforce desired pro-recovery behaviors, including A&D group attendance, meeting with medical providers, and presenting for long-acting injectable medication administration.

  4. How to encourage clients to meet with clinicians, adhere to medications, or abstain from methamphetamine? Benefits: Better Physical and Mental Health Improved Relationships Social Productivity

  5. To clients, the benefits of treatment plan adherence can be long-term, and therefore less immediate, than other competing factors Benefits: Better Physical and Mental Health Improved Relationships Social Productivity

  6. In service of Long Term Benefit Competing Forces Meeting with clinicians Negative symptoms, disruptive to daily life Medication adherence Avoiding side effects, a nuisance to remember Abstinence from methamphetamine, cannabis, or other substances Cravings, Avoidance of withdrawal, Desired alteration in perception of symptoms or difficult life circumstances

  7. A way to bring positive consequences for treatment adherence forward in time and to make them: More immediate More salient More predictable

  8. Based on Operant Behavioral Principles, also known as Instrumental Learning or Operant Conditioning If I do this, then that happens

  9. OPERANT CONDITIONING CLASSICAL CONDITIONING Stimuli that are present when a behavior is rewarded (or punished) affect the likelihood of the behavior in the future a thought process Stimuli that signal significant events produce reflexive behavior - often outside conscious awareness e.g., Salivating at the sight of your favorite treat! e.g., Getting to the ACT meeting early because you know there will be donuts and the best ones go fast!

  10. A chance at free cannabis entices someone to enter a cannabis dispensary. Winning free cannabis makes it more likely an ACT client will return for another chance to win free cannabis

  11. Contingency Management uses immediate positive reinforcers to improve adherence to treatment plan elements that might otherwise have mostly long-term benefits.

  12. Target a behavior that you can reinforce in real time (not a delayed reward) Attending an appointment with a clinician Attending a group Successfully providing a laboratory sample (regardless of result) Appropriate Urine Drug Screen (point of care is best for immediacy of results)

  13. The reinforcers have to be valuable to the participants (but they don t have to be expensive). Ask participants what they want! Adolescents often don t want CDs, for example I d rather give health food, but participants often desire less nutritious snacks Can allow participants to bank points for larger items they would like

  14. VOUCHER-BASED PRIZE-BASED

  15. VOUCHER-BASED PRIZE-BASED Half the prizes are verbal encouragement, some are worth a little, a few are worth a bit more, and one can be pretty nice Works equally well as a fixed paradigm, and is cheaper to run Does NOT contribute to development or/ relapse to Gambling Disorder FUN! Reinforcement is always the same, no chance involved

  16. An Escalating Schedule can be applied to either Fixed or Intermittent reinforcement structures to improve efficacy (escalating works better!) Number of reinforcers increases with each successive successful behavior (up to a maximum), until participant misses an opportunity to display the desired behavior

  17. CONSTANT ESCALATING First: 1 Misses one: 0 First: 1 Second in a row: 1 Misses one: 0 First: 1 Second in a row: 1 Third in a row: 1 Fourth in a row: 1 Fifth in a row: 1 Sixth in a row: 1 Seventh in a row: 1 First: 1 Misses one: 0 First: 1 Second in a row: 2 Misses one: 0 First: 1 Second in a row: 2 Third in a row: 3 Fourth in a row: 4 Fifth in a row: 5 Sixth in a row: 5 Seventh in a row: 5

  18. Continue to reinforce the behavior with contingency management at least until the long-term benefit of the behavior has been realized, and perhaps longer.

  19. This might be a long time, but why not? If it was worth it to start, continuing is worth it Instead of stopping a reinforcer that is working, add a new behavioral target to a successful program for a given participant

  20. Sell it to your administrators by showing how the cost of the program could be offset by a decrease in lost productivity: Missed appointments with your psychiatrist or other internal medical providers Low productivity due to missed groups or sessions with other providers

  21. Decide fixed vs intermittent (cheaper) Decide constant vs escalating (better) Decide how many will participate Decide how many target behaviors per participant How many chances per month for a participant to demonstrate a target behavior for a reinforcement? Calculate (average) value of reinforcement

  22. Initial Monthly Budget = Participants x Monthly Opportunities to show target behavior x Value E.g., 20 ACT clients can earn a $1 by meeting with their Psychiatrist twice a month, attending a weekly A&D group, or coming for their monthly long-acting injectable medication nurse appointment =20 x (2+4+1) x $1 = $140

  23. Initial Monthly Budget = Participants x Monthly Opportunities to show target behavior x Value x highest consistency multiplier E.g., 20 ACT clients can earn a $1 by meeting with their Psychiatrist twice a month, attending a weekly A&D group, or coming for their monthly long-acting injectable medication nurse appointment. They can earn up to 5 $1 bills if they attend five or more in a row. =20 x (2+4+1) x $1 x 5 = $700

  24. Initial Monthly Budget = Participants x Monthly Opportunities to show target behavior x Average Prize Value E.g., 20 ACT clients can earn a prize by meeting with their Psychiatrist twice a month, attending a weekly A&D group, or coming for their monthly long-acting injectable medication nurse appointment. The Average Prize value is $0.50 =20 x (2+4+1) x $0.50 = $70

  25. Divide the total value of all possible prizes by the total number of chances to win a prize. Ignore the free spin slots

  26. 16 terminal slots 8 are free 5 are worth 100 points 2 are worth 200 points 1 is worth 500 points (0+500+400+500)/16 =$0.87 average if 100 points is a dollar Ignore the free spin slots

  27. Initial Monthly Budget = Participants x Monthly Opportunities to show target behavior x highest consistency multiplier x Average Prize Value E.g., 20 ACT clients can earn a prize by meeting with their Psychiatrist twice a month, attending a weekly A&D group, or coming for their monthly long-acting injectable medication nurse appointment. They can earn up to 5 spins if they attend five or more in a row. The Average Prize value is $0.50. =20 x (2+4+1) x 5 x $0.50 = $350

  28. These calculations have given us an idea of where to start with an initial budget, but operating costs will be much lower (unless everyone is perfect all the time!) Use actual expenditures over the first several months to make future budgets. If you have more funding than you are spending, add more behavioral targets or improve value of prizes.

  29. Medium sized ACT Team Methamphetamine, Cannabis, and Alcohol Use complicate response to treatment Tobacco-related illness will cause the death of most consumers of specialty mental health services We wanted to increase engagement in treatment

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