Bipolar Disorder in Older Adults

 
Bipolar disorder in older
adults
 
Tier 3
 
Bipolar disorder in older adults
 
Bipolar disorder - episodes of mania along with episodes of depression.
Some of these individuals would have been diagnosed with bipolar disorder
when they were younger and some get diagnosed after the age of 50 years.
Older adults account for only 0.1-0.5% of Bipolar disorder in the community
but the risks of admission to hospital are high and account for 4-8% of
admissions.
The mean age of onset of Bipolar disorder in older adults is around 50 years
of age.
It is more common in females than in males.
It can be missed as the person can present with more functional impairment
and cognitive impairment.
 
Symptoms
 
Symptoms of mania can include
Excessive energy
Inability to sleep
Racing thoughts
Pressured speech
Excessive spending or reckless
behaviour
Inability to concentrate
Grandiose ideas
Delusional thoughts
Hallucinations
 
Symptoms of depression can include
Sleep disturbance - early morning waking
Fatigue
Psychomotor retardation
Loss of interest
Poor memory
Hopelessness
Ideas of guilt
Suicidal thoughts
 
Difference between later onset bipolar
disorder and early onset bipolar diso
rder
 
Differential diagnosis
 
Early stages of dementia can present with symptoms suggestive of
mania such as irritable mood, emotional lability, sleep disturbance,
and impaired social judgment
Delirium
Alcohol and drug misuse/ withdrawals
Medications such as steroids, Parkinson’s medications, anti-
hypertensive medications such as captopril, and antidepressants
can precipitate mania
Physical causes - thyroid issues including hyperthyroidism,
infections, metabolic disturbances, neoplasm, stroke, encephalitis,
epilepsy and toxins can precipitate mania
 
Impact of having Bipolar disorder on older
adults
 
Higher rates of cardiovascular disease
 
Diabetes and Hypertension are more common
 
Higher rates of cognitive issues
 
Symptoms as a result of being on medications eg lithium - tremor of
hands
 
Death occurs an average of 10 years earlier than the general
population.
 
Assessment
 
Detailed history including details of the onset of the symptoms,
progression, fluctuations of mood, impact on functioning, sleep
changes, irritability, appetite changes, weight loss
Past history of bipolar affective disorder or recurrent depressive
episodes which have been refractory to treatment
Medications and recent changes / compliance
Use of alcohol and drugs
Physical health history and current symptoms
Risk taking behaviours including risk of suicide, driving etc
Collateral history from carers and partners including impact on
them
 
Risks to watch out for
 
Wandering risk / going out late in the night or early hours
Not eating / drinking - self-neglect
Risky behaviour - excessive spending / excessive alcohol intake
Driving
Non-compliance with medications including physical health
medications
Loss of support network due to disorganised / odd behaviour
Vulnerability to exploitation
Risk of suicide
 
Investigations
 
Investigations include detailed blood tests
 
CT / MRI scan to rule out neoplasms, infections, lumbar puncture
may be needed
 
Alcohol and drug history / screening
 
Treatment
 
Treatment would include referral to an Old Age Psychiatrist
Medications such as mood stabilisers and anti-psychotic medications can
help with regulation of the mood
Anti-depressants can be used for depression along with mood stabilisers
If they are on Lithium make sure that they have information leaflet
about lithium and how physical ill health can impact on lithium levels
Regular monitoring of serum lithium levels (12 hrs post-dose every 3
months) and yearly calcium levels
Try to reduce any psychosocial stressors
Encourage understanding of their illness and need for treatment
Psychological therapies may be useful
 
 
 
Monitoring
 
Check medication packs to check for compliance as they may not
believe they are unwell .Monitor for side effects.
If at all possible liaise with a family member to ensure that they
are alerted and know who to call in a crisis
Ask the older person  about their Sleep - Advise re sleep hygiene
Check on their Hydration - Are they drinking enough fluids?
Check on their Nutrition - Are they eating enough?
Monitor risks -Ensure that the patient is safe
 
 
Resources
 
MPC_09_01 - Bipolar Disorder | Bipolar Disorder
(mindedforfamilies.org.uk)
 
 
This is an easy to access website for older adults and their families
which has good advice  about  symptoms and treatment of Bipolar
disorder in older adults
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Bipolar disorder in older adults can have a later onset, often after the age of 50, with episodes of mania and depression. Recognizing symptoms like excessive energy, inability to sleep, and cognitive impairment is crucial. Late-onset bipolar disorder differs from early-onset in familial illness rates, medical morbidity associations, and relapse rates. The differential diagnosis includes early dementia stages, delirium, substance misuse, and physical causes like thyroid issues. Proper diagnosis and management are essential for elderly individuals with bipolar disorder.

  • Bipolar Disorder
  • Older Adults
  • Mania
  • Depression
  • Late-Onset

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  1. Bipolar disorder in older adults Tier 3

  2. Bipolar disorder in older adults Bipolar disorder - episodes of mania along with episodes of depression. Some of these individuals would have been diagnosed with bipolar disorder when they were younger and some get diagnosed after the age of 50 years. Older adults account for only 0.1-0.5% of Bipolar disorder in the community but the risks of admission to hospital are high and account for 4-8% of admissions. The mean age of onset of Bipolar disorder in older adults is around 50 years of age. It is more common in females than in males. It can be missed as the person can present with more functional impairment and cognitive impairment.

  3. Symptoms Symptoms of mania can include Excessive energy Inability to sleep Racing thoughts Pressured speech Excessive spending or reckless behaviour Inability to concentrate Grandiose ideas Delusional thoughts Hallucinations Symptoms of depression can include Sleep disturbance - early morning waking Fatigue Psychomotor retardation Loss of interest Poor memory Hopelessness Ideas of guilt Suicidal thoughts

  4. Difference between later onset bipolar disorder and early onset bipolar disorder Late onset Bipolar disorder Early onset Bipolar disorder Develops around the age of 50 years or later Usually before the age of 40 years Lower rate of familial illness Higher rate of familial illness Higher rate of neurological and medical morbidity Not associated with higher rates of neurological or medical morbidity Higher rates of relapses Although there are relapses, the rates of relapses are not as high as in late onset

  5. Differential diagnosis Early stages of dementia can present with symptoms suggestive of mania such as irritable mood, emotional lability, sleep disturbance, and impaired social judgment Delirium Alcohol and drug misuse/ withdrawals Medications such as steroids, Parkinson s medications, anti- hypertensive medications such as captopril, and antidepressants can precipitate mania Physical causes - thyroid issues including hyperthyroidism, infections, metabolic disturbances, neoplasm, stroke, encephalitis, epilepsy and toxins can precipitate mania

  6. Impact of having Bipolar disorder on older adults Higher rates of cardiovascular disease Diabetes and Hypertension are more common Higher rates of cognitive issues Symptoms as a result of being on medications eg lithium - tremor of hands Death occurs an average of 10 years earlier than the general population.

  7. Assessment Detailed history including details of the onset of the symptoms, progression, fluctuations of mood, impact on functioning, sleep changes, irritability, appetite changes, weight loss Past history of bipolar affective disorder or recurrent depressive episodes which have been refractory to treatment Medications and recent changes / compliance Use of alcohol and drugs Physical health history and current symptoms Risk taking behaviours including risk of suicide, driving etc Collateral history from carers and partners including impact on them

  8. Risks to watch out for Wandering risk / going out late in the night or early hours Not eating / drinking - self-neglect Risky behaviour - excessive spending / excessive alcohol intake Driving Non-compliance with medications including physical health medications Loss of support network due to disorganised / odd behaviour Vulnerability to exploitation Risk of suicide

  9. Investigations Investigations include detailed blood tests CT / MRI scan to rule out neoplasms, infections, lumbar puncture may be needed Alcohol and drug history / screening

  10. Treatment Treatment would include referral to an Old Age Psychiatrist Medications such as mood stabilisers and anti-psychotic medications can help with regulation of the mood Anti-depressants can be used for depression along with mood stabilisers If they are on Lithium make sure that they have information leaflet about lithium and how physical ill health can impact on lithium levels Regular monitoring of serum lithium levels (12 hrs post-dose every 3 months) and yearly calcium levels Try to reduce any psychosocial stressors Encourage understanding of their illness and need for treatment Psychological therapies may be useful

  11. Monitoring Check medication packs to check for compliance as they may not believe they are unwell .Monitor for side effects. If at all possible liaise with a family member to ensure that they are alerted and know who to call in a crisis Ask the older person about their Sleep - Advise re sleep hygiene Check on their Hydration - Are they drinking enough fluids? Check on their Nutrition - Are they eating enough? Monitor risks -Ensure that the patient is safe

  12. Resources MPC_09_01 - Bipolar Disorder | Bipolar Disorder (mindedforfamilies.org.uk) This is an easy to access website for older adults and their families which has good advice about symptoms and treatment of Bipolar disorder in older adults

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