Bioinformatics Tools and Data Storage Requirements

SOM Lecture Committee
David Buchner, Chair
  
Dept of Genetics
  
2024
Drew Adams
   
Dept of Genetics
  
2023
Neil Greenspan
  
Dept of Pathology
  
2025
Pratima Sood
   
Dept of Medicine-VA
  
2024
Sichun Yang
   
Dept of Nutrition
  
2023
Presentation to the Faculty Council, Dec 2022
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In addition to the lectures, the SOM Lecture Committee was able to reconnect with many members of the Bloomfield
family, including 5 of the grandchildren of Louis Bloomfield. One member of the family was able to attend the 2022
lecture in person and other members were able to view the lecture via zoom. The date for the 2023 lecture has been
shared with the family so that they can continue to attend future lectures and reinvigorate their relationship with
CWRU.  
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Lecture from “distinguished foreign visitors so that they might be attracted here to give lectures in the medical
sciences”
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- Committed speakers to date: Damian Young (Baylor)
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Support an annual lecture from “an outstanding individual who has achieved or been involved in the achievement of a
significant advance in medicine or a closely related field”
2022:
 The Burton funds will be used to support a lecture by Dr. Geoffrey Greene from the University of Chicago. The
2022 lecture was postponed due to COVID given the preference for an in-person seminar. The lecture will now be held
in April 2023. Dr Greene is best known for his studies into the mechanisms and therapeutics of breast and prostate
cancer. Dr. Greene is a AAAS Fellow and has been recognized for his work by the Susan Komen foundation, the North
American Menopausal Society, and the Endocrine Society.
2023:
 Plans are in the works for a symposium celebrating the 20
th
 anniversary of the sequencing of the human
genome in the fall of 2023. The symposium will be jointly hosted by CWRU and the Cleveland Museum of Natural
History.
Confirmed 
thus 
far: Sarah Tishkoff
 (
UPENN); Heidi Rehm
 (
Broad); David Goldstein (Actio Biosciences). Fall 2023
In addition to these lectures, funds were used from the Burton Fund to support a research symposium jointly
organized by Drs. Mark Chance, Robert Kirsch, and Robert Bonomo. The symposium took place August 18-19, 2022
at CWRU. The focus of the symposium was Department of Defense Themed Biomedical Research. Matching funds
were provided by the Center for Translational Science Collaborative and the Center for Proteomics and Bioinformatics.
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This content provides insights into utilizing bioinformatics tools, operating systems, and storage solutions for processing sequencing data efficiently. It covers the need for a computer system to run various bioinformatics tools like aligners, assemblers, and variant callers, along with requirements for creating documents and presentations. Additionally, it delves into the storage specifications required to handle large amounts of genomic data generated from sequencing procedures. The content also touches upon using a Linux cluster for real analysis jobs, Illumina and Nanopore sequencing techniques, and processing sequence data for alignment and variant calling.

  • Bioinformatics
  • Sequencing Data
  • Computer System
  • Storage Solutions
  • Genomic Analysis

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  1. SOM Lecture Committee David Buchner, Chair Dept of Genetics 2024 Drew Adams Neil Greenspan Pratima Sood Dept of Genetics Dept of Pathology Dept of Medicine-VA 2023 2025 2024 Sichun Yang Dept of Nutrition 2023 Presentation to the Faculty Council, Dec 2022

  2. Louis A. Bloomfield Memorial Lecture Provide lectures in Greater Cleveland by distinguished medical Scientists and scholars 2022: The Bloomfield lecture fund was used to support a lecture and visit by Dr. Jeff Friedman from HHMI and The Rockefeller University on 9/21/22. Dr. Friedman is best known for the discovery of Leptin and the mechanism by which leptin regulates appetite. Dr. Friedman has been recognized by many awards including the Breakthrough Prize in Life Sciences, Wolf Prize in Medicine, Lasker Award, Harrington Prize for Innovation in Medicine, and Shaw Prize for Life Sciences and Medicine. 2023: The Bloomfield lecture fund will be used to support a lecture and visit by Dr. Tom Sudhof from HHMI and Stanford University on 3/13/23. Dr. Sudhof is best known for his work on neurotransmitter release and synaptic transmission for which he was awarded the Lasker Award and the Nobel Prize. In addition to the lectures, the SOM Lecture Committee was able to reconnect with many members of the Bloomfield family, including 5 of the grandchildren of Louis Bloomfield. One member of the family was able to attend the 2022 lecture in person and other members were able to view the lecture via zoom. The date for the 2023 lecture has been shared with the family so that they can continue to attend future lectures and reinvigorate their relationship with CWRU.

  3. H.M. Hanna Lecture Fund Lecture from distinguished foreign visitors so that they might be attracted here to give lectures in the medical sciences 2022: The Hanna fund was used to support a zoom lecture by Dr. Benjamin Lewin on 2/9/22. Dr. Lewin founded the journal Cell and wrote a definitive textbook in the field of genetics titled GENES. 2023: Plans are in the works for a symposium focused on chemical biology. - Committed speakers to date: Damian Young (Baylor)

  4. Courtney Burton Frontiers of Medicine Lecture Fund Support an annual lecture from an outstanding individual who has achieved or been involved in the achievement of a significant advance in medicine or a closely related field 2022: The Burton funds will be used to support a lecture by Dr. Geoffrey Greene from the University of Chicago. The 2022 lecture was postponed due to COVID given the preference for an in-person seminar. The lecture will now be held in April 2023. Dr Greene is best known for his studies into the mechanisms and therapeutics of breast and prostate cancer. Dr. Greene is a AAAS Fellow and has been recognized for his work by the Susan Komen foundation, the North American Menopausal Society, and the Endocrine Society. 2023: Plans are in the works for a symposium celebrating the 20thanniversary of the sequencing of the human genome in the fall of 2023. The symposium will be jointly hosted by CWRU and the Cleveland Museum of Natural History. Confirmed thus far: Sarah Tishkoff (UPENN); Heidi Rehm (Broad); David Goldstein (Actio Biosciences). Fall 2023 In addition to these lectures, funds were used from the Burton Fund to support a research symposium jointly organized by Drs. Mark Chance, Robert Kirsch, and Robert Bonomo. The symposium took place August 18-19, 2022 at CWRU. The focus of the symposium was Department of Defense Themed Biomedical Research. Matching funds were provided by the Center for Translational Science Collaborative and the Center for Proteomics and Bioinformatics.

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