Overview of Virology Methods: Cultivation, Isolation, Purification
Various methods are employed in virology, including virus cultivation in different cells, virus isolation, and virus purification through centrifugation. Structural investigations, virion component-based techniques, and virus infectivity-based techniques are also common in virology research. Underst
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Adenoviruses: Structure, Replication, and Epidemiology
Adenoviruses, known for causing respiratory infections, have at least 41 serotypes categorized into 6 subgenera. Their structure includes 252 capsomeres, 240 hexons, and specific proteins for attachment. The replication involves virus attachment, penetration, uncoating, and transportation of viral D
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Potential of Tat-Based Therapeutic Vaccine in HIV Treatment
A phase 1 clinical trial is underway for a Tat.Oyi-based therapeutic vaccine targeting the virulence factor Tat in HIV. Tat plays a crucial role in viral gene expression and immune system modulation. Inhibiting Tat could disrupt the viral life cycle, block virion release, and potentially reactivate
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Overview of Virus Structure and Classification
Viruses were first observed by Edward Jenner in 1798, who noticed their role in providing immunity. They are smaller than bacteria and consist of genetic material surrounded by a protein coat. Viruses are obligate cellular parasites, replicating only inside living cells. The structure of viruses inc
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Nipah Virus: A Comprehensive Overview
Nipah virus, belonging to the Paramyxoviridae family, is a zoonotic virus with high pathogenicity and mortality rates. It falls under the Henipavirus genus, known for infecting a wide range of animal species. Its virion structure consists of non-segmented, negative-sense RNA, and the viral genome co
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