Surgical Prophylaxis and Antimicrobial Selection Guidelines in Surgery
Surgical prophylaxis involves administering antibiotics before contamination of previously sterile tissues to prevent infections. Common pathogens in surgical site infections include skin flora like S. aureus. Antimicrobial selection is based on the surgical procedure, likely pathogens, and safety c
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Updated Vancomycin Collaborative Practice Guidelines in 2020
Vancomycin guidelines updated in 2020 include transitioning from trough-based to AUC-based monitoring, emphasizing achieving an AUC/MIC of 400-600 for improved outcomes. Major updates involve loading dose adjustments, targeting AUC/MIC instead of trough levels, and pharmacist-orderable MRSA nasal sw
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Updated Guidelines and Practices for Vancomycin Therapy
The consensus guidelines for vancomycin therapy have been updated in 2020, focusing on switching from trough-based to AUC-based monitoring. Achieving an AUC/MIC of >400 within the first 48 hours is linked to better outcomes in serious MRSA infections. Changes include a new loading dose, therapeutic
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