Understanding the Molecular Biology of Cancer: Insights into Cell Transformation and Tumorigenesis
Normal cells undergo defined lifespan processes, but disruptions in cell differentiation and apoptosis can lead to cancer development. Unchecked cell growth caused by genetic mutations results in tumors that can metastasize. Cancer is a multistep disease involving genetic changes, and major transfor
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Organoid Models for Neuroendocrine Cell Growth and Tumorigenesis
Research presented at the ENETS 2020 virtual meeting discussed the generation of organoids from lung, intestinal, and pancreatic neuroendocrine neoplasms (NENs) to study normal neuroendocrine cells and their transformation to NENs. The success rate in generating organoids was higher for lung NENs co
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