The ALIGN.AR trial evaluates Trilogy THV system in high-risk patients with severe aortic regurgitation. Untreated AR is linked to high mortality, emphasizing the need for safe alternative interventions like TAVR devices. The study aims to demonstrate safety and effectiveness of the Trilogy valve in

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This presentation explores the evolution of Trans-Catheter Aortic Valve Replacement (TAVR), highlighting historical milestones, anatomical considerations, the role of Balloon Aortic Valvuloplasty, current guidelines, the need for TAVI, and a notable case study by Dr. Cribier. The content discusses t

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The presentation discusses various endpoints in aortic valve development and Transcatheter Aortic Valve Replacement (TAVR) trials, including comparisons, study stages, and newer devices. It covers different trial populations, primary and secondary endpoints, and the evaluation of non-inferiority. Su

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This study aims to evaluate the safety and efficacy of transcatheter aortic valve replacement (TAVR) in low-risk patients with bicuspid aortic valve stenosis. TAVR with Evolut valves has shown promising results in tricuspid aortic stenosis, but data on bicuspid cases are lacking. The participating s

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Investigating reoperations after native and valve-in-valve transcatheter aortic valve replacement (TAVR), this study analyzes characteristics and implications, noting a higher frequency in valve-in-valve cases. Data on demographics and trends in reoperation rates shed light on the outcomes of these

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TAVR has shown promising outcomes in tricuspid aortic stenosis but has not been extensively studied in low-risk bicuspid patients. The Low Risk Bicuspid Trial aims to evaluate the procedural and short-term outcomes of TAVR in this patient population through a prospective study involving 25 centers.

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The article discusses the sufficiency of TAVR centers from the viewpoint of a heart team comprising interventional cardiologists and cardiac surgeons. It explores case studies, national coverage determinations, valve selection choices, and guidelines related to aortic aneurysms and aortic valve repl

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