Propofol is a widely used IV hypnotic with a unique mechanism of action involving GABA receptors and dopamine modulation. Its history, from initial anaphylactic reactions to current emulsion formulations, is intriguing. Understanding its pharmacokinetics, including metabolism in the liver and kidney

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This comprehensive guide delves into the use of sedatives, analgesics, and paralytics in the intensive care unit (ICU). It covers various medications like Etomidate, Propofol, Ketamine, Benzodiazepenes, and Dexmedetomidine, detailing their indications, dosages, and effects. Understanding the role of

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