Understanding Polio Eradication Efforts and Vaccine Development
Polio, a disabling disease caused by the poliovirus, mainly affects children and can lead to paralysis. Efforts to eradicate polio include the development of vaccines like the Inactivated Polio Vaccine (IPV) and Oral Polio Vaccine (OPV). The poliovirus' choice of host, ease of transmission, and impa
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Poliovirus Transmission Risk Assessment and Investigation Overview
This document provides a comprehensive risk assessment for poliovirus transmission, including details on virus isolates, epidemiological contexts, mapping of new detections, and detailed case investigations. It focuses on VDPV detections and past outbreaks, offering insights for response strategies.
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Enhancing AFP Surveillance for Polio Eradication in East Africa
This presentation discusses the importance of Acute Flaccid Paralysis (AFP) surveillance in detecting poliomyelitis cases, with a focus on the National Stop Transmission of Polio Mission in Kasese District, Uganda. The goal is to eradicate poliovirus through strategies such as immunization campaigns
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Implementation of nOPV2 for cVDPV2 Outbreak Response
Circulating Vaccine-Derived Poliovirus (cVDPV) outbreaks, particularly cVDPV type 2 (cVDPV2), have increased in recent years. The novel oral polio vaccine type 2 (nOPV2) is an innovative tool developed over nearly 10 years to combat these outbreaks. Clinical trials have shown that nOPV2 provides com
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Understanding Polio: Causes, Spread, and Eradication Efforts
Polio, a disabling and life-threatening disease caused by the poliovirus infection, can spread through contact with infected feces or droplets from sneezes/coughs. It mainly affects children, potentially leading to paralysis or respiratory issues. Lack of clean water and sanitation contributes to it
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Understanding Poliomyelitis: Causes, Symptoms, and Prevention
Poliomyelitis, commonly known as polio, is an infectious viral disease caused by the poliovirus. It primarily affects young children, leading to the destruction of motor neurons. The disease can manifest with varying symptoms, ranging from mild flu-like symptoms to severe paralysis. Poliovirus is tr
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