Stay updated on the latest advancements in Haem Genomics and Germline Findings. Learn about changes in MPN Panel testing and Genomics TATs. Explore the benefits and improvements in SNP Array testing.

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The PSI Data Science SIG, established in 2017, comprises a group of Data Scientists and Statisticians focusing on various topics like Genomics, Machine Learning, and more. They aim to collaborate on data science in drug development, engage with regulatory bodies, and explore new data analysis method

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The genomic medicine field is advancing rapidly, with a focus on enhancing healthcare services through genomic testing for prediction, prevention, diagnosis, and precision medicine. The NHS is actively integrating genomics into its healthcare system, aiming for equitable access to genomic testing. I

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Explore the world of genome assembly, shotgun sequencing, and the fundamental concepts behind deriving genomes from large sets of sequencing reads. Learn about the complexity and core algorithms involved in contemporary genome assembly processes. Discover how the shotgun concept has revolutionized g

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Explore the CNT tool enabling semi-automatic translation from Common Workflow Language (CWL) to Nextflow for genomics workflows. Understand the benefits, challenges, and workflow execution aspects for efficient genomics pipeline development and automation.

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Explore the intersection of statistical genomics, machine learning, and artificial intelligence through topics like knowledge mining, MMAP algorithm, cloud computing, and historical events such as Garry Kasparov vs IBM Deep Blue. Delve into the concepts of statistical learning methods, data predicti

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Pharmacokinetics, as explained in a lecture by Oula Mohammed Sami, M.B.Ch.B/MSc in clinical pharmacology, delves into how the body processes drugs, contrasting with pharmacodynamics which focuses on drug actions. Key topics covered include properties influencing treatment outcomes, the significance

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Explore the historical roots of pharmacology from ancient civilizations like India, China, and Egypt. Learn about the development and principles of drug activity, including pharmacokinetics and pharmacodynamics. Discover early medicinal practices and the evolution of drug administration. Gain insigh

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Delve into the Genetics and Genome Evolution (GGE) Bioinformatics for Genomics Lecture Series 2022 presented by Sven Bergmann. Explore topics like RNA-seq, differential expression analysis, clustering, gene expression data analysis, epigenetic data analysis, integrative analysis, CHIP-seq, HiC data,

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The falling costs of sequencing have revolutionized various fields like genetics, genomics, cell biology, microbiology, and evolutionary biology. Sequencing data has enabled us to understand genomes, revolutionize cell biology techniques, conduct comparative genomics, population genomics, and metage

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Delve into the world of genetics and genomics through the lens of integrative biology, investigating the differences between cell types, the rationale for gene expression profiling, and the analysis of differential gene expression in various diseases. Uncover the significance of gene ontology, co-ex

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This chapter discusses the classification, salient features, and uses of sedatives and hypnotics in veterinary pharmacology. Sedatives subdue excitement and induce calmness without necessarily causing sleep, while hypnotics induce and maintain sleep. Both classes of drugs act as CNS depressants and

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Explore the pharmacology of the autonomic nervous system focusing on cholinergic and adrenergic agents. Learn about cholinomimetics, direct and indirect acting cholinergic agonists, their therapeutic indications, and adverse effects. Discover the mechanism of action and uses of nicotinic agonists. D

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This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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Cephalosporins are a group of semisynthetic antibiotics derived from cephalosporin C obtained from a fungus. This chapter covers the introduction, chemistry, properties, solubility, classification, spectrum of activity, mechanism of action, applications, and side effects of cephalosporins. They offe

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Corticosteroids are steroid hormones produced by the adrenal cortex, classified into glucocorticoids and mineralocorticoids. Glucocorticoids have diverse effects on metabolism, immune responses, and inflammation, whereas mineralocorticoids regulate electrolyte balance. Mechanistically, corticosteroi

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Fish pharmacology is crucial for treating fish diseases effectively using drugs. Factors like water quality, pathogens, mortality rate, legal aspects, and economics need consideration. Different routes of drug administration in fish include water medication, immersion or dipping, hyperosmotic infilt

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Neurohumoural transmission in the field of veterinary pharmacology involves the communication of nerve messages through the release of chemical messengers. This process includes axonal conduction and junctional transmission. The historical aspects of neurohumoural transmission highlight key discover

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Cholinergic neurons play a vital role in neurotransmission by utilizing acetylcholine (ACh) as a neurotransmitter. This neurotransmission involves steps like synthesis, storage in vesicles, release, receptor binding, degradation, and recycling of choline and acetate. Choline acetyltransferase cataly

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Non-steroidal anti-inflammatory drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic effects. They act primarily on peripheral pain mechanisms and have limited CNS effects. NSAIDs have a long history dating back to the use of White Willow bark, and the

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The regulation of respiration involves sensory and efferent pathways, with afferent pathways comprising stretch receptors, C-fibres, and irritant receptors, while efferent pathways include parasympathetic and sympathetic nerves. Cough physiology is a protective reflex initiated by various stimuli to

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Understanding the mechanism of ovulation and hormonal regulation is key in classifying drugs used to induce ovulation. This lecture covers the pharmacology of different groups of drugs, their mechanisms of action, administration protocols, indications, efficacy rates, and adverse effects. Antiestrog

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Genomics Market by Technology (Sequencing, Microarray, PCR, Nucleic Acid Extraction), Application (Drug Discovery, Diagnostic, Research), End User (Pharmaceutical, Hospital, Academic), Offering (Instrument, Consumables, Software) - Global Forecast to

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Delve into the realm of bacterial comparative genomics with insights on terminologies, assembly methods, annotation processes, and two key approaches to microbial genomics. Explore the basics of genomics terminology, assembly-based and variant-based analyses, as well as annotation methods for protei

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Phasing in personal genomics involves resolving haplotypes from diploid genotypes to identify associations with diseases, compound heterozygosity, shared haplotypes, and ancestral origins. It helps in detecting relatives, historical recombination events, and haplotypes under selection. Different typ

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Dive into the world of the parasympathetic nervous system and cholinergic pharmacology, exploring concepts like cholinomimetics, parasympathomimetics, cholinolytics, and more. Discover how acetylcholine synthesis and degradation play crucial roles in these processes, and learn about different cholin

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Explore the concepts of random variables, covariance matrix, special matrices, and self-defined functions in statistical genomics through a series of homework questions. Gain insights into linear algebra and statistical genomics while working on Homework 1, analyzing the expectation and variance of

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ELISA (Enzyme-Linked Immunosorbent Assay) is a vital immunological technique used in detecting antigens or antibodies in samples. This article covers the types of ELISA tests, such as Direct, Indirect, and Sandwich, along with the principles and applications of ELISA in diagnosis. The process involv

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This toolkit provides essential resources for healthcare professionals involved in genomics services, covering topics such as genomic medicine, whole genome sequencing, clinical genetic testing methods, interpretation of DNA variants, and more. It also details the specific sample requirements for di

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Explore student experiences in learning tricky concepts in pathology and pharmacology as part of a veterinary medicine program. Discover challenges faced, valuable resources created, and the importance of student perspectives in enhancing learning outcomes.

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Explore the essential aspects of pharmacology and toxicology covered in Investigator Brochures, including nonclinical information, safety pharmacology, general toxicology, genetic toxicology, and more. Learn about the significance of pharmacology in predicting intended and unintended effects, consid

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Genetics 210 is a course focused on personalized medicine and genomics designed for MDs, PhDs, and curious students. The course covers topics such as genotyping, informed consent, and exploring specific genetic loci. Students engage in projects like annotating genomes and debating FDA regulations. T

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Developmental pharmacology in children involves unique considerations such as drug metabolism, urine concentration, and muscle relaxant dosing. The field faces challenges with limited drug testing in pediatric populations, emphasizing the importance of age-appropriate pharmacotherapy. Factors like d

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The study of ocular pharmacology involves understanding general pharmacological principles, pharmacodynamics, and pharmacokinetics. Drugs can be delivered to ocular tissue locally via eye drops, ointments, injections, or systemically through oral or intravenous routes. Factors such as drug concentra

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Explore a wide array of experimental expectations in genomics research, including types of expectations, nature of samples and data, processing efficacy, sources of variation, unexpected findings, raw data expectations, RNA contamination, biological assumptions in gene knockout experiments, expected

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Understanding the pharmacology of heart failure with reduced ejection fraction is crucial as it impacts millions of Americans and poses significant healthcare costs. The complex pathophysiology involves mechanisms like the Frank-Starling mechanism, alterations in myocyte regeneration, neurohumoral s

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Delve into the fascinating world of genetics and genomics in healthcare, pondering questions about disease outcomes, familial health patterns, and personalized treatment strategies. Discover the shift towards a more precise and tailored approach to healthcare through genetic testing, ethical conside

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Exploring the evolution of statistical genomics techniques, this lecture delves into the history of FarmCPU and BLINK, addressing challenges in GWAS and the development of models like PC+SNP+e and PC+Kinship+e. It also covers popular software packages in the field and the importance of moving beyond

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Explore the intricate world of ocular pharmacology with Dr. Ajai Agrawal, an Additional Professor at A.I.I.M.S., Rishikesh. The learning objectives cover pharmacokinetics, pharmacodynamics, and various routes of drug administration in ocular treatments. Delve into the anatomy of the eye, tear film c

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Delve into the world of genomics and bioinformatics through the Genetics and Genome Evolution (GGE) lecture series by Sven Bergmann. Explore topics such as RNA-seq analysis, differential expression, gene expression measurement techniques, and integrative analysis with epigenetic data. Gain insights

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