Haem Genomics update
Stay updated on the latest advancements in Haem Genomics and Germline Findings. Learn about changes in MPN Panel testing and Genomics TATs. Explore the benefits and improvements in SNP Array testing.
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Latest Developments in Genomic Medicine and NHS Genomic Strategy
The genomic medicine field is advancing rapidly, with a focus on enhancing healthcare services through genomic testing for prediction, prevention, diagnosis, and precision medicine. The NHS is actively integrating genomics into its healthcare system, aiming for equitable access to genomic testing. I
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Semi-Automatic Translation from CWL to Nextflow for Genomics Workflows
Explore the CNT tool enabling semi-automatic translation from Common Workflow Language (CWL) to Nextflow for genomics workflows. Understand the benefits, challenges, and workflow execution aspects for efficient genomics pipeline development and automation.
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Statistical Genomics and Machine Learning Challenges in AI
Explore the intersection of statistical genomics, machine learning, and artificial intelligence through topics like knowledge mining, MMAP algorithm, cloud computing, and historical events such as Garry Kasparov vs IBM Deep Blue. Delve into the concepts of statistical learning methods, data predicti
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Understanding Pharmacokinetics in Clinical Pharmacology
Pharmacokinetics, as explained in a lecture by Oula Mohammed Sami, M.B.Ch.B/MSc in clinical pharmacology, delves into how the body processes drugs, contrasting with pharmacodynamics which focuses on drug actions. Key topics covered include properties influencing treatment outcomes, the significance
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Historical Development and Principles of Pharmacology
Explore the historical roots of pharmacology from ancient civilizations like India, China, and Egypt. Learn about the development and principles of drug activity, including pharmacokinetics and pharmacodynamics. Discover early medicinal practices and the evolution of drug administration. Gain insigh
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Bioinformatics for Genomics Lecture Series 2022 Overview
Delve into the Genetics and Genome Evolution (GGE) Bioinformatics for Genomics Lecture Series 2022 presented by Sven Bergmann. Explore topics like RNA-seq, differential expression analysis, clustering, gene expression data analysis, epigenetic data analysis, integrative analysis, CHIP-seq, HiC data,
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Transformative Power of Sequencing in Molecular Biology
The falling costs of sequencing have revolutionized various fields like genetics, genomics, cell biology, microbiology, and evolutionary biology. Sequencing data has enabled us to understand genomes, revolutionize cell biology techniques, conduct comparative genomics, population genomics, and metage
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Exploring Genetics and Genomics in Integrative Biology
Delve into the world of genetics and genomics through the lens of integrative biology, investigating the differences between cell types, the rationale for gene expression profiling, and the analysis of differential gene expression in various diseases. Uncover the significance of gene ontology, co-ex
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Overview of Sedatives and Hypnotics in Veterinary Pharmacology
This chapter discusses the classification, salient features, and uses of sedatives and hypnotics in veterinary pharmacology. Sedatives subdue excitement and induce calmness without necessarily causing sleep, while hypnotics induce and maintain sleep. Both classes of drugs act as CNS depressants and
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Pharmacology of the Autonomic Nervous System Part 2 Summary and Learning Objectives
Explore the pharmacology of the autonomic nervous system focusing on cholinergic and adrenergic agents. Learn about cholinomimetics, direct and indirect acting cholinergic agonists, their therapeutic indications, and adverse effects. Discover the mechanism of action and uses of nicotinic agonists. D
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Renal Pharmacology: Drug Excretion and Renal Clearance Questions
This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID
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Overview of Cephalosporins in Veterinary Pharmacology
Cephalosporins are a group of semisynthetic antibiotics derived from cephalosporin C obtained from a fungus. This chapter covers the introduction, chemistry, properties, solubility, classification, spectrum of activity, mechanism of action, applications, and side effects of cephalosporins. They offe
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Understanding Pharmacology of Corticosteroids by Dr. Saeed Ahmed
Corticosteroids are steroid hormones produced by the adrenal cortex, classified into glucocorticoids and mineralocorticoids. Glucocorticoids have diverse effects on metabolism, immune responses, and inflammation, whereas mineralocorticoids regulate electrolyte balance. Mechanistically, corticosteroi
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Understanding Routes of Drug Administration in Fish Pharmacology
Fish pharmacology is crucial for treating fish diseases effectively using drugs. Factors like water quality, pathogens, mortality rate, legal aspects, and economics need consideration. Different routes of drug administration in fish include water medication, immersion or dipping, hyperosmotic infilt
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Understanding Neurohumoural Transmission in Veterinary Pharmacology
Neurohumoural transmission in the field of veterinary pharmacology involves the communication of nerve messages through the release of chemical messengers. This process includes axonal conduction and junctional transmission. The historical aspects of neurohumoural transmission highlight key discover
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Understanding Cholinergic Neurons and Agonists in Pharmacology
Cholinergic neurons play a vital role in neurotransmission by utilizing acetylcholine (ACh) as a neurotransmitter. This neurotransmission involves steps like synthesis, storage in vesicles, release, receptor binding, degradation, and recycling of choline and acetate. Choline acetyltransferase cataly
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Overview of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Veterinary Pharmacology
Non-steroidal anti-inflammatory drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic effects. They act primarily on peripheral pain mechanisms and have limited CNS effects. NSAIDs have a long history dating back to the use of White Willow bark, and the
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Understanding Respiratory System Pharmacology and Cough Physiology
The regulation of respiration involves sensory and efferent pathways, with afferent pathways comprising stretch receptors, C-fibres, and irritant receptors, while efferent pathways include parasympathetic and sympathetic nerves. Cough physiology is a protective reflex initiated by various stimuli to
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Pharmacology of Ovulation-Inducing Drugs
Understanding the mechanism of ovulation and hormonal regulation is key in classifying drugs used to induce ovulation. This lecture covers the pharmacology of different groups of drugs, their mechanisms of action, administration protocols, indications, efficacy rates, and adverse effects. Antiestrog
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Genomics Market Projected to Reach $70.52 Billion by 2031, Driven by Advancements in Genomic Technologies
Genomics Market by Technology (Sequencing, Microarray, PCR, Nucleic Acid Extraction), Application (Drug Discovery, Diagnostic, Research), End User (Pharmaceutical, Hospital, Academic), Offering (Instrument, Consumables, Software) - Global Forecast to
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Understanding Bacterial Comparative Genomics: A Comprehensive Overview
Delve into the realm of bacterial comparative genomics with insights on terminologies, assembly methods, annotation processes, and two key approaches to microbial genomics. Explore the basics of genomics terminology, assembly-based and variant-based analyses, as well as annotation methods for protei
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Understanding Phasing in Personal Genomics
Phasing in personal genomics involves resolving haplotypes from diploid genotypes to identify associations with diseases, compound heterozygosity, shared haplotypes, and ancestral origins. It helps in detecting relatives, historical recombination events, and haplotypes under selection. Different typ
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Understanding the Parasympathetic Nervous System and Cholinergic Pharmacology
Dive into the world of the parasympathetic nervous system and cholinergic pharmacology, exploring concepts like cholinomimetics, parasympathomimetics, cholinolytics, and more. Discover how acetylcholine synthesis and degradation play crucial roles in these processes, and learn about different cholin
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Statistical Genomics Lecture 5: Linear Algebra Homework Questions
Explore the concepts of random variables, covariance matrix, special matrices, and self-defined functions in statistical genomics through a series of homework questions. Gain insights into linear algebra and statistical genomics while working on Homework 1, analyzing the expectation and variance of
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Understanding ELISA Techniques in Cellular and Molecular Pharmacology
ELISA (Enzyme-Linked Immunosorbent Assay) is a vital immunological technique used in detecting antigens or antibodies in samples. This article covers the types of ELISA tests, such as Direct, Indirect, and Sandwich, along with the principles and applications of ELISA in diagnosis. The process involv
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Genomics Facilitator's Toolkit Summary & Sample Requirements
This toolkit provides essential resources for healthcare professionals involved in genomics services, covering topics such as genomic medicine, whole genome sequencing, clinical genetic testing methods, interpretation of DNA variants, and more. It also details the specific sample requirements for di
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Understanding Pharmacology and Toxicology in Investigator Brochures
Explore the essential aspects of pharmacology and toxicology covered in Investigator Brochures, including nonclinical information, safety pharmacology, general toxicology, genetic toxicology, and more. Learn about the significance of pharmacology in predicting intended and unintended effects, consid
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Genetics 210: Personalized Medicine and Genomics Course Overview
Genetics 210 is a course focused on personalized medicine and genomics designed for MDs, PhDs, and curious students. The course covers topics such as genotyping, informed consent, and exploring specific genetic loci. Students engage in projects like annotating genomes and debating FDA regulations. T
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Understanding and Validating Experimental Expectations in Genomics Research
Explore a wide array of experimental expectations in genomics research, including types of expectations, nature of samples and data, processing efficacy, sources of variation, unexpected findings, raw data expectations, RNA contamination, biological assumptions in gene knockout experiments, expected
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Exploring Genetics and Genomics in Healthcare
Delve into the fascinating world of genetics and genomics in healthcare, pondering questions about disease outcomes, familial health patterns, and personalized treatment strategies. Discover the shift towards a more precise and tailored approach to healthcare through genetic testing, ethical conside
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Advancements in Statistical Genomics: FarmCPU and Method Development
Exploring the evolution of statistical genomics techniques, this lecture delves into the history of FarmCPU and BLINK, addressing challenges in GWAS and the development of models like PC+SNP+e and PC+Kinship+e. It also covers popular software packages in the field and the importance of moving beyond
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Understanding Genomics and Bioinformatics in Genetics Evolution
Delve into the world of genomics and bioinformatics through the Genetics and Genome Evolution (GGE) lecture series by Sven Bergmann. Explore topics such as RNA-seq analysis, differential expression, gene expression measurement techniques, and integrative analysis with epigenetic data. Gain insights
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Understanding Power, Type I Error, and FDR in Statistical Genomics
Explore concepts of statistical genomics in Lecture 11 focusing on power, type I error, and false discovery rate (FDR) in GWAS analysis. The content covers simulations of phenotype from genotype data, GWAS by correlation, resolution and bin approach, and implications on QTN bins for power and error
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Update on Irish Government's Beef Data Genomics Programme
The spending review for 2022 provides key findings and recommendations on the Beef Data Genomics Programme in Ireland. The analysis shows positive trends in genetic gain, with recommendations for a new iteration focusing on data-driven schemes and holistic approaches to improve sector sustainability
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Exploring the Fascinating World of Pharmacology: From Historical Developments to Basic Principles
Uncover the rich history of pharmacology from ancient civilizations to modern times, tracing the origins of medicinal practices and the development of drug-related concepts. Delve into the fundamental areas of pharmacology, including pharmacokinetics and pharmacodynamics, to understand the mechanism
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Genomics Market to Reach $70.52 Billion by 2031, Driven by Rising Demand for Personalized Medicine
Genomics Market by Technology (Sequencing, Microarray, PCR, Nucleic Acid Extraction), Application (Drug Discovery, Diagnostic, Research), End User (Pharmaceutical, Hospital, Academic), Offering (Instrument, Consumables, Software) - Global Forecast to
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Spatial Genomics Market
Meticulous Research\u00ae, a top global market research firm, has released a report titled \"Spatial Genomics Market by Type (Genomics, Transcriptomics), Technology (Sequencing, Imaging), Application (Oncology, Neurology), Offering (Consumables, Inst
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Introduction to Microarray Technology in Functional Genomics
Functional genomics involves analyzing large datasets from biological experiments, such as gene expression analysis using microarray technology. DNA arrays facilitate probing and quantifying nucleic acid species in solution. However, the use of microarrays is being replaced by high throughput sequen
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Genomics Market to Reach $70.52 Billion by 2031
Genomics Market by Technology (Sequencing, Microarray, PCR, Nucleic Acid Extraction), Application (Drug Discovery, Diagnostic, Research), End User (Pharmaceutical, Hospital, Academic), Offering (Instrument, Consumables, Software) - Global Forecast to
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