Patient Nicole Thomason, a 50-year-old female, presented with memory concerns and progressive cognitive decline. Initial imaging showed subtle changes, while recent PET CT revealed marked hypometabolism in specific brain regions indicative of advanced neurodegenerative disorder, potentially Alzheime

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Alzheimer's disease is a prevalent neurodegenerative brain disorder characterized by memory loss and other cognitive impairments. This article discusses the etiology, risk factors, and pathophysiology of Alzheimer's disease, along with in-vitro screening models used to test potential drugs, focusing

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Parkinsonism encompasses a group of progressive syndromes with symptoms such as bradykinesia, tremors, and rigidity. Parkinson's Disease is the most common form, but there are various classifications including primary and secondary causes. Pathologically, it involves the loss of dopaminergic neurons

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Parkinson's disease is a neurodegenerative disorder that impacts dopamine levels in the brain. The history, epidemiology, causes, and pathophysiology of the disease are explored, shedding light on its significant impact on the nervous system. Genetic and environmental factors play a role in the deve

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Explore the fundamentals of AYUSH (Ayurveda, Yoga, Unani, Siddha, and Homeopathy) through a comprehensive introduction by Dr. Vartika Saxena. Delve into topics ranging from allergic diseases, neurodegenerative conditions, and cancers to psychological and psychiatric issues. Discover the importance o

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Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease affecting motor neurons, leading to muscle weakness and various symptoms. This case study focuses on Judy, a 52-year-old woman diagnosed with ALS, detailing her symptoms, progression, exercise routine, assistive device us

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The ADNI Private Partner Scientific Board (PPSB) Update for 2015 highlights key leadership, partner organizations, deliverables, and accomplishments in advancing drug development. Susan De Santi as Chairperson, along with industry leaders, plays a crucial role in advising and collaborating with ADNI

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This detailed summary provides information on significant brain-related project datasets and consortia, including PsychENCODE, BrainSpan, CommonMind Consortium, AMP-AD Knowledge, and more. Each dataset or consortium focuses on specific areas such as genomics, neuropsychiatric diseases, neurodegenera

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Subacute or chronic fatal neurodegenerative disease in adult cattle, Bovine Spongiform Encephalopathy (BSE) is a transmissible spongiform encephalopathy with spongy degeneration in the CNS. It is caused by an infectious protein called prion and is mostly found in Europe, with potential zoonotic impa

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Multiple sclerosis (MS) is a neurodegenerative disease affecting millions globally by causing myelin loss in the CNS axons. This study investigates the role of NF155 raft association in the inflammatory response of microglial cells, shedding light on potential treatment strategies for MS. Liposome t

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The Pathological Protein delves into the intriguing case of Stephen Churchill, a young man whose sudden decline and tragic death spark questions about his mysterious neurological condition. As the investigation unfolds, more puzzling cases emerge, shedding light on the enigmatic world of neurodegene

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Clinical research in dermatology in Scotland faces challenges and opportunities, led by experts like Dr. Richard Weller and Prof. David Crossman. The Chief Scientists Office (CSO) plays a key role in supporting high-quality health research in Scotland, fostering partnerships with NHS Research Scotla

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Comparison of DTI protocols and measures in 317 participants revealed strong associations with age and cognitive impairment. MD and TDF-FA emerged as best measures, with robust connections to age. NODDI in advanced MRI allows for differentiation of A-beta positive and negative groups, offering great

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