Recent Developments on the Geroprotective Potential of Metformin in Human Studies
Recent human studies highlight the geroprotective potential of metformin in various conditions such as type II diabetes and cancer. Metformin has shown benefits in reducing all-cause mortality, macrovascular effects, and increased survival rates. However, concerns about study design and replication
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Advancing Healthy Aging and Longevity Through Geroscience Research
Utilizing the geroscience paradigm, researchers explore targeting aging processes to extend healthspan and lifespan. The TAME Aging Outcomes Trial aims to test this hypothesis with metformin, a drug that shows promise in impacting aging-related pathways. By focusing on delaying the onset of multiple
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Evolution of Glucose-Lowering Therapies in Primary Care Settings
Cardiovascular effects of older glucose-lowering therapies and the history of cardiovascular outcome trials are discussed in this educational slide module. It outlines the timeline of treatment options from the discovery of insulin to the introduction of various medications. Evidence regarding the c
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