Lipoprotein and Atherosclerosis
Understand the correlation between lipoprotein metabolism imbalance and the development of atherosclerosis. Learn about LDL and HDL cholesterol metabolism, receptor-mediated endocytosis, and the role of lipoprotein(a).
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Evolution in HDL Hypothesis: CSL-112 Infusions in Acute Myocardial Infarction
This study explores the use of CSL-112 infusions in patients with acute myocardial infarction to enhance high-density lipoprotein (HDL) function. By focusing on improving HDL-C function through ApoA-1 infusions, the research aims to enhance outcomes associated with cardiovascular events. The efficac
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Understanding Lipoproteins: Structures and Functions
Lipoproteins are compound lipids formed by the aggregation of neutral and amphipathic lipids with proteins (apoproteins). They serve as vehicles for transporting lipids through the bloodstream and lymphatic system, acquiring polarity due to their hydrophilic properties. These macromolecules are synt
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Baseline Lipoprotein(a) Levels in Statin-Treated Patients for Cardiovascular Event Prediction
Lipoprotein(a) levels play a crucial role in cardiovascular disease risk assessment, especially in patients undergoing statin therapy. This individual patient-data meta-analysis from the Lancet explores the predictive value of lipoprotein(a) levels in 29,069 patients across seven landmark statin tri
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Understanding the Morphology and Genome Organization of NDV
NDV, a pleomorphic virus, has an irregular spherical shape with filamentous features. Its genome consists of a single-stranded RNA with six genes arranged in a specific order. The virus contains a lipoprotein envelope with short spikes and a helical nucleocapsid core to protect the RNA. The genomic
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