Methotrexate-Related Leukoencephalopathy in a Teenager with T-cell ALL

A 16-year-old female with T-cell ALL presented with acute right-sided weakness and slurred speech. Differential diagnoses included stroke, asparaginase toxicity, viral infections, and methotrexate neurotoxicity. Imaging revealed an area of restricted diffusion in the centrum semiovale, characteristi

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