A 22-year-old female patient with a history of infected endocarditis and recent dental procedure presents with high-grade fever, chills, shortness of breath, and arthralgia. Examination reveals a pan systolic murmur and tachycardia. Echocardiography shows mitral regurgitation with vegetation on the

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Infections can be transmitted through skin and mucous membranes via direct or indirect human contact, as well as from non-human sources. The infective agents include viruses, bacteria, fungi, and arthropods. Factors like high population density, poor hygiene, and host behavior play crucial roles in

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Explore the role of rescue therapy in COPD management, including the use of antibiotics and steroids, to address exacerbations and improve quality of life. Learn about the benefits, guidelines, and criteria for identifying patients who may benefit from home rescue courses. Discover how antibiotic th

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Zoonoses, diseases that can be transmitted from animals to humans, are classified based on etiological agents, transmission cycle, and reservoir hosts. Etiological agents include bacteria, viruses, rickettsial, chlamydial, mycotic, and parasitic organisms. The transmission cycle categorizes zoonoses

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Infective endocarditis is an infection of the heart's endocardial surface that can be classified into four groups. It is crucial to recognize common bacteria causing IE, understand clinical presentations, diagnostic methods, and management strategies. The pathophysiology involves turbulent blood flo

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Heartworm infection in dogs is caused by infective larvae that mature into adult worms, leading to potential complications such as pulmonary arterial wall thickening and increased right heart pressure. Clinical signs may include tiredness, shortness of breath, and weight loss. Diagnosis involves ant

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Toxocara canis, also known as the Arrow-headed worm, is a parasite commonly found in dogs, particularly in puppies less than six months old. This article explores the general characteristics, life cycle, transmission routes, and prenatal infections of Toxocara canis. From the appearance of the male

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The Community Intravenous Therapy (IVT) Team in Gloucestershire offers outpatient antibiotic therapy services, accepting referrals from GPs, consultants, doctors, and specialist nurses. Changes to the service, details on antibiotic choices, frequently treated infective conditions, and contact inform

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Cestodes, commonly known as tapeworms, are long segmented worms with distinct morphology found in the small intestine. This comprehensive guide covers Diphyllobothrium latum, Taenia saginata, their life cycles, morphology, clinical manifestations, diagnosis, and prevention strategies. Detailed infor

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Infective diseases such as blackquarter, brucellosis, and foot and mouth disease pose significant threats to cattle health and food safety. Blackquarter is a fatal disease caused by Clostridium chauvaei, while brucellosis leads to contagious abortion in cattle. Foot and mouth disease is highly conta

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Trichostrongyle transmission primarily occurs through pasture contamination with eggs shed by adult worm populations in grazing hosts. The development of infective larvae on pasture involves specific conditions like moisture and warmth, leading to different types of ostertagiasis infections. Various

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An active heroin user with endocarditis raises the question - should the patient stay in the hospital for IV therapy or be discharged with oral antibiotics? A randomized trial explores the feasibility of switching to oral antibiotics with similar outcomes. Inclusion criteria detail stability require

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An 11-year-old girl presented with a four-month history of fever, three months of generalized weakness and body ache, and a recent weight loss. Physical examination revealed pallor, edema, generalized tenderness, lymphadenopathy, and telangiectatic rash. Vitals showed elevated respiratory and heart

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Infective Endocarditis (IE) is a microbial infection of the heart's endothelial surface or valves. Streptococci and Staphylococci are common causative agents. Predisposing conditions include heart defects and valve diseases. IE presents with symptoms like fever, heart murmurs, and petechiae. Diagnos

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Salmonella bacteria, often transmitted through contaminated food or drink, can cause various infections in humans and animals. They are identified by their morphology, and classified into different species and subtypes. The pathogenesis of Salmonella infections varies, with some species infective pr

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Porcine Reproductive & Respiratory Syndrome (PRRS) is caused by an RNA virus from the Arteriviridae family, susceptible to environmental factors like temperature, pH, and exposure to detergents. The virus exhibits genomic variability, leading to different levels of virulence and clinical symptoms in

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Neisseria gonorrhoeae, also known as gonococcus, is a bacterial pathogen responsible for gonorrhea. The virulence factors of N. gonorrhoeae include pili/fimbriae for adhesion, outer membrane proteins like Porin for protection, opacity-associated protein for adhesion to neutrophils, and more. Clinica

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Chemotherapy involves using chemical agents to destroy infective agents and inhibit the growth of cancerous cells, while antimicrobials and antibiotics are used to treat various infections. Anticancer agents, antiprotozoals, and anthelminthics are specific types of drugs used for managing diseases.

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Explore the intricate details of the heart, including its chambers, external features, myocardium, valves, and fibrous skeleton. Delve into the layers of the heart wall, the pericardium, and the fibrous skeleton. Learn about the different layers of the myocardium in the atria and ventricles, as well

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Ascaris lumbricoides, commonly known as roundworm, is a human parasite found in the intestine. The life cycle involves copulation, egg development, and infection of a new host through ingestion of eggs. It does not require an intermediate host. The larval stages undergo migration within the body. Th

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Pyrexia of unknown origin (PUO) is a challenging diagnostic scenario characterized by persistent fever without an identified cause. Dr. Sujeetha Chandrababu M.D. defined PUO as temperatures exceeding 38.3°C for several weeks with no definitive diagnosis. Classification of PUO includes various categ

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