INTRODUCTION OF IMMUNOLOGY
Explore the fundamentals of immunology with insights into immunogens, antigens, epitopes, and haptens. Uncover how these key components play vital roles in shaping immune responses and learn about paratopes, the basis of immunogenicity, and the key events that determine foreignness in the immune sys
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Understanding Antigens and Immunogenicity in Immunology
Learn about antigens, immunogenicity, antigenicity, and epitopes in immunology. Antigens are substances with distinct immunologic properties, while immunogenicity refers to the ability of an antigen to induce an immune response. Antigenicity is the ability of an antigen to combine specifically with
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Effect of Efgartigimod on Humoral Vaccine Responses in Patients with Autoimmune Diseases
The study explores the impact of Efgartigimod, a Neonatal Fc Receptor blocker, on humoral vaccine responses in patients with autoimmune diseases. It discusses how immunosuppressive therapies used in autoimmune disorders may affect susceptibility to infections and impair vaccine immunogenicity, highl
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Nonparametric Tolerance Interval Approach to Immunogenicity Assay Cut Point Determination
This content discusses the importance of determining the cut point for immunogenicity assays to detect anti-drug antibodies (ADA) in large-molecule therapeutics. It highlights the need for well-developed and validated assays to ensure drug efficacy and safety. The approach involves multiple-tiered v
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