Update on Malaria Libre Project Meeting - 19th April 2023
The Malaria Libre Project Meeting held on 19th April 2023 discussed key topics such as the Aryl Imidazole chemical series, potential new series, and the MMV Early Lead Criteria for the next milestone. Chemistry resources appointed by MMV were also outlined, focusing on Aryl Imidazoles as the main ar
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Understanding Antifungal Drugs: Modes of Action and Applications
Antifungal drugs target ergosterol biosynthesis in fungi, disrupting cell membrane integrity. Imidazoles like miconazole and ketoconazole are commonly used for skin infections, while triazoles such as fluconazole treat systemic yeast infections. Allylamines inhibit ergosterol synthesis, with terbina
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Understanding Azole Antifungal Agents for Veterinary Use
Azole antifungal agents play a crucial role in treating fungal infections in veterinary medicine. Imidazoles like clotrimazole and triazoles like fluconazole are commonly used for their fungistatic properties. These agents inhibit fungal enzymes, disrupting membrane fluidity and inhibiting cell repl
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