Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare blood disorder characterized by the destruction of red blood cells in the bloodstream, leading to anemia, hemoglobinuria, jaundice, and other symptoms. It is often challenging to diagnose due to its rarity. PNH can be a thrombophilic state, causing

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Bilirubin, a yellow compound in the catabolic pathway, plays a crucial role in health. Estimating serum bilirubin levels is key in diagnosing conditions like jaundice. Elevated levels, above 2 mg/dl, can indicate disease. Jaundice, characterized by skin and eye discoloration, has pre-hepatic, hepati

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Post-Parturient Haemoglobinuria (PPH) is a metabolic disease affecting high-producing dairy cows and buffaloes. It is characterized by intravascular hemolysis, hemoglobinuria, and anemia. The condition is mainly caused by phosphorus deficiency, ingestion of certain plants, and increased phosphorus r

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Packed cell volume (PCV) is a measure of the percentage of blood volume occupied by red blood cells (RBCs), used to screen for anemia and calculate hemoglobin concentration. Also known as hematocrit (HCT), it falls within specific ranges for adult males and females. The PCV is determined from venous

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Blood matching for patients is crucial to prevent adverse reactions like hemolysis and death. ABO and RhD compatibility testing are fundamental, along with selecting antigen-negative units for patients with clinically significant antibodies. Beyond mandatory requirements, matching can be complex due

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Post-Parturient Haemoglobinuria (PPH) is a metabolic disease affecting high-producing dairy cows after calving, characterized by hemolysis, hemoglobinuria, and anemia. Common in buffaloes and cows, it is caused by phosphorus deficiency in diet, affecting intracellular functions and leading to clinic

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Streptococci are diverse Gram-positive bacteria found in nature, some of which are part of the human microbiota while others cause diseases. This article discusses the morphology, classification, hemolysis properties, Lancefield grouping, and details about Streptococcus pyogenes, a significant human

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Streptococci are Gram-positive cocci commonly found in chains or pairs. This article covers their classification based on hemolysis patterns and Lancefield grouping, along with general characteristics and principles of differentiation tests. Learn about the infections caused by different Streptococc

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Cold agglutinin disease, a rare form of autoimmune hemolytic anemia, accounts for 15% of AIHA cases. Implementing a cold agglutinin screen for diagnosis can have significant financial implications in healthcare costs. This condition is characterized by the presence of cold agglutinins, primarily IgM

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This presentation by Dr. Archana explores the terminology, sources, toxicokinetics, mechanisms of toxicity, clinical signs, and treatment options related to copper toxicity in animals. It discusses how copper absorption, retention, and elimination are affected by dietary factors, leading to copper a

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This presentation delves into the critical topic of blood compatibility for safe transfusions, covering aspects such as ABO and Rh blood groups, clinically significant antibodies, and potential incompatibilities. The session aims to enhance understanding of antigens, antibodies, and the risks of mis

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