Human Immunodeficiency Virus
HIV, a member of the lentivirus subfamily of retroviruses, causes Acquired Immunodeficiency Syndrome (AIDS). HIV-1 and HIV-2 have distinct characteristics, with HIV-1 being global and HIV-2 primarily in West Africa. The virus encodes reverse transcriptase and has an envelope containing glycoproteins
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Understanding the Role of V3 Region in HIV Entry to CD4 T-Cells
The V3 region of gp120 plays a crucial role in HIV entry to CD4 T-cells by determining the coreceptor usage. Studies focus on the structural aspects of V3, its conservation, coreceptor binding, and antibody accessibility. The HIV envelope structure, including trimeric spikes with gp120 and gp41 glyc
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