The history of chemotherapy is divided into three phases, starting from the empirical use of compounds in ancient times to the modern era marked by targeted drug development. Ehrlich's pioneering work in the late 19th to early 20th centuries laid the foundation for understanding the selective toxici

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Edward Jenner initiated the concept of vaccination by discovering that cowpox could confer immunity to smallpox. Paul Ehrlich differentiated blood cells, proposed the side chain hypothesis, and pioneered serum therapy and chemotherapy. Elie Metchnikoff developed the cellular theory of immunity, advo

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