The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

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Explore the world of seizures and epilepsy to enhance your knowledge and learn how to provide optimal support for individuals with epilepsy. Discover the basics of seizures, signs to watch out for, the difference between seizures and epilepsy, and common causes of seizures. Empower yourself with ess

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Electroconvulsive Therapy (ECT), also known as electroshock, is a psychiatric treatment that induces seizures in anesthetized patients for therapeutic purposes. ECT has a controversial history but is well-established in the medical field. Introduced in 1938, ECT has replaced older treatments like in

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Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

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Epilepsy is a group of disorders characterized by recurrent, unprovoked seizures. Seizures are sudden surges of electrical activity in the brain that can cause alterations in sensation, behavior, or consciousness. They can be classified as partial or generalized based on their origin and clinical ma

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Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

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This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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ICD-10-CM codes play a crucial role in diagnosing and managing seizure disorders, including epilepsy and non-epileptic seizures. This detailed guide covers the coding guidelines for various types of seizures, such as intractable epilepsy and conversion disorder with seizures. It also explains how th

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Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

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The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

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A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

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Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

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The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

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People living with epilepsy face challenges regarding driving, as seizures can pose a serious risk. Laws and regulations vary by state, requiring individuals to be seizure-free for a specific period. Teenagers with epilepsy may desire independence through driving, prompting discussions on seizure ma

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Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

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In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

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Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

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Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

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Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

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Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

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Seizures of both plant-based and synthetic New Psychoactive Substances (NPS) declined in 2018, along with a decrease in global seizures of khat and fluctuations in the use of NPS. Legislation on substances like mephedrone led to a decline in their use, while the use of ketamine increased. NPS use va

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Neonatal seizures are sudden changes in neurologic function of a newborn, involving motor, behavior, and autonomic functions. The pathophysiology includes delays in Na/K ATPase maturation, increased receptor density, and GABAergic transmission. Different types of seizures like subtle, clonic, tonic,

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Anticonvulsant drugs play a crucial role in managing epilepsy, a common neurological disorder characterized by recurrent seizures. This article discusses the classification of epileptic seizures, mechanisms of action of anticonvulsants, and the role of GABA A receptors as targets for anticonvulsant

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In this case study, a 2-year-old male presenting with developmental delay and seizures was evaluated for a CNV at the 12p13.1p12.3 region. The CNV was found to overlap with the GRIN2B gene, a known haploinsufficient gene associated with developmental disorders. Despite potential additional scoring c

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Seizure disorders can have varying symptoms and may occur at any time in life. Immediate medical treatment is crucial for the first seizure. Factors like stress, illness, temperature changes, and photosensitivity can impact seizure thresholds. Different types of seizures, including focal aware tonic

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The National Association of Drug Diversion Investigators (NADDI) focuses on combating prescription drug diversion through advocacy, training, and collaboration with law enforcement. They address the misuse of opioids like OxyContin and Oxycodone, showing successes in reducing diversion and deaths in

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The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

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Neonatal seizures are a critical sign of neurologic dysfunction in newborns, with various types such as subtle, clonic, tonic, spasms, and myoclonic seizures. The immature brain's excitability and differences from the mature brain predispose neonates to seizures. Generalized clonic seizures are rare

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Epilepsy is a medical disorder characterized by recurrent, unprovoked seizures. Seizures are sudden alterations in perception or behavior caused by abnormal neuronal activity. The incidence of epilepsy is high in early childhood, declines, plateaus, and then rises among the elderly. Seizures can be

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This practical guide provides valuable insights into seizures and epilepsy for primary care providers, covering topics such as different seizure types, epilepsy definition and treatment initiation, antiseizure medications, and status epilepticus management. Terminology and a clinical scenario are di

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This informational content delves into various aspects of seizures and comas, covering topics such as the prevalence of seizures, classification of epilepsy, EEG in epilepsy, seizure history, and different types of seizures like simple partial and complex partial seizures. It provides insights into

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Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

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Epilepsy is a common neurological disorder characterized by unprovoked seizures, affecting a significant portion of the population. Enhancing the diagnosis and prediction of seizures through EEG recordings can improve therapeutic strategies for epilepsy patients. Functional connectivity analysis in

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Sheffield Teaching Hospitals NHS Foundation Trust offers a specialist neurology psychotherapy service for patients with functional neurological symptoms. The service, established in 2003, provides brief psychotherapy sessions to patients referred by consultant neurologists. The approach includes stu

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A series of scenarios involving pediatric patients experiencing seizures at home or upon arrival in the Emergency Department are presented. Each case outlines the administration of benzodiazepines, the timing of seizures, and the patient's eligibility for enrollment in a randomized study based on sp

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This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

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Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

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Seizure disorders in children can be caused by various factors such as brain development issues, brain injuries, infections, and more. Triggers like stress, lack of sleep, and certain lifestyle habits can lead to seizures. There are different types of seizures, including tonic-clonic, absence, myocl

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The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

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The content highlights significant events related to international drug control efforts, emphasizing the launch of the INCB Annual Reports, the UNGASS session at the United Nations, and the focus on health, welfare, and challenges in combating drug abuse. It discusses issues such as new psychoactive

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