The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

1 views • 25 slides

Explore the potential of targeting human exosomes using a bispecific antibody platform, enhancing drug delivery capabilities. The study delves into engineering exosomes as drug carriers, developing exosome targeting antibodies (ExTAbs), and verifying exosome delivery efficiency. Future directions in

7 views • 12 slides

Injectable peptide-like hydrogels offer a novel approach for sustained drug delivery over extended periods. This technology, developed by Dr. Garry Laverty, aims to improve patient adherence by providing a convenient and effective long-acting formulation. The hydrogel, formed in situ, allows for sus

2 views • 8 slides

Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

0 views • 28 slides

Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

0 views • 33 slides

This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

0 views • 55 slides

Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

0 views • 35 slides

In the modern era, herbal drugs offer a safer alternative to synthetic molecules with fewer side effects. However, their efficacy can vary due to fluctuating concentrations of active constituents. Novel Drug Delivery Systems (NDDS) such as liposomes, niosomes, and microspheres play a crucial role in

0 views • 30 slides

The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

1 views • 46 slides

A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

0 views • 17 slides

Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

0 views • 17 slides

The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

0 views • 49 slides

Therapeutic Drug Monitoring (TDM) utilizes pharmacokinetic principles to optimize drug therapy by balancing efficacy and toxicity levels. Historical background reveals a shift from empirical dosing to precise pharmacokinetic analysis, aiming to minimize toxicity risks and maximize therapeutic benefi

0 views • 47 slides

Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

0 views • 9 slides

In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

11 views • 10 slides

Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

0 views • 21 slides

Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

0 views • 24 slides

Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

0 views • 29 slides

Understanding pH-solubility profiles of drugs like indomethacin, chlorpromazine, and oxytetracycline is crucial in formulating pharmaceuticals. Factors affecting dissolution rates, such as particle size and solubility, can be optimized to enhance drug absorption. Different methods like particle size

0 views • 46 slides

Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

0 views • 29 slides

This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t

2 views • 20 slides

Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

5 views • 45 slides

Institute of Laser for Postgraduate Studies at the University of Baghdad, led by Assist. Prof. Dr. Lutfi Ghulam Awazli, focuses on laser delivery systems in surgical procedures. The systems discussed include optical fibers, articulated arms, hollow waveguides, and free beams. Optical fibers, compose

0 views • 10 slides

Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

3 views • 17 slides

Erythrocytes, the main carriers of oxygen in the body, can be utilized as carriers for drug delivery due to their biocompatibility and ability to protect drugs from premature degradation. They offer advantages such as targeted drug delivery, sustained release of drugs, and protection against toxic e

1 views • 30 slides

The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware

3 views • 9 slides

This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

0 views • 28 slides

The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

1 views • 17 slides

Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

0 views • 12 slides

The presentation by Charles Gore, Executive Director of Medicines Patent Pool, at IAS 2019 discussed how the MPP works to ensure future access to innovative drug formulations and delivery mechanisms. The MPP model involves negotiating public health-driven licenses with patent holders, sublicensing t

0 views • 16 slides

This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

0 views • 8 slides

Ocular pharmacology faces challenges in effective drug delivery due to blood-retinal, blood-aqueous, and blood-vitreous barriers that impede high drug concentrations in the eye. Various routes of administration, including topical and local injections, are employed to overcome these barriers. Pharmac

0 views • 27 slides

Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.

0 views • 7 slides

Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

0 views • 8 slides

The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

0 views • 19 slides

Azole therapeutic drug monitoring (TDM) is crucial for managing antifungal therapy due to factors like drug interactions, compliance issues, disease severity, and pharmacokinetic variability. This monitoring helps ensure optimal drug levels are maintained for effective treatment. Different TDM metho

0 views • 18 slides

The content highlights significant events related to international drug control efforts, emphasizing the launch of the INCB Annual Reports, the UNGASS session at the United Nations, and the focus on health, welfare, and challenges in combating drug abuse. It discusses issues such as new psychoactive

0 views • 13 slides

This study explores the effects of analgesic treatments crossed with gender on pain levels. The data analysis includes factors such as gender and drug type, and the statistical model examines pain index as a linear function of factor levels. The ANOVA results indicate significant effects of gender,

0 views • 17 slides

Explore the quantitative aspects of drug action, including drug receptor binding, dose-response curves, therapeutic utility, and types of antagonism. Learn about drug affinity, efficacy, potency, and the relationship between drug binding and concentration. Discover how concentration-binding curves a

0 views • 18 slides

Side effects of medications in the acute setting can manifest as impairments in various body systems, including integumentary, musculoskeletal, cardiovascular/pulmonary, and neuromuscular systems. Factors influencing adverse drug events include pharmacokinetics, drug interactions, and patient-specif

0 views • 24 slides