Drug bioavailability - PowerPoint PPT Presentation


Strategic Differentiation for a New Drug in a Crowded Market

We, at Jasper Colin, stepped in to help them create a strategic positioning for their new drug, ensuring it stood out in a competitive landscape. Our strategic positioning efforts gave the drug a competitive edge, making it a preferred choice among European physicians.\n\nRead the full report to div

4 views • 6 slides


Understanding Graded Dose-Response Relationships in Pharmacodynamics

Graded dose-response relationships in pharmacodynamics involve how drug effects depend on concentrations at receptor sites. The potency and efficacy of drugs can be determined through these relationships. Potency refers to the amount of drug needed for a specific effect, while efficacy relates to th

0 views • 32 slides



OPTHALMIC PREPARATION

Ophthalmic preparations are essential for eye health, and their formulation requires careful consideration of factors like tonicity, pH adjustment, viscosity-imparting agents, stabilizers, antioxidants, surfactants, and preservatives. The goal is to ensure stability, bioavailability, and efficacy wh

1 views • 14 slides


Air Force Drug Demand Reduction Program Overview

This document provides insights into the Air Force Drug Demand Reduction Program's objectives, governing directives, testing procedures, and the mission to maintain a drug-free environment. It highlights the various types of drug testing, commander roles, and the program's commitment to safeguarding

0 views • 14 slides


Age-Friendly App: Managing Drug-Drug Interactions Between Prescriptions and OTC Analgesics

The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

1 views • 25 slides


Long-Acting Injectable Peptide-Like Hydrogel for Sustained Drug Delivery

Injectable peptide-like hydrogels offer a novel approach for sustained drug delivery over extended periods. This technology, developed by Dr. Garry Laverty, aims to improve patient adherence by providing a convenient and effective long-acting formulation. The hydrogel, formed in situ, allows for sus

2 views • 8 slides


Excipients Market: Integration with Nanotechnology for Targeted Drug Delivery

In 2022, The Global Excipients Market size accounted for USD 5.1 billion. This market is estimated to reach USD 8.9 billion in 2032 at a CAGR of 5.9% between 2023 and 2032.\n\nExcipients Market Overview:\n\nThe excipients market is experiencing robust growth driven by the increasing demand for pharm

3 views • 3 slides


TEAP Program Overview and Confidentiality in Job Corps

TEAP, the Trainee Employee Assistance Program, aims to assist young adults in developing employability skills while promoting a drug-free environment at Job Corps. The program provides education, prevention activities, drug testing, and support for students in need. Confidentiality of information, i

2 views • 20 slides


Midterm Review of International Drug Policy Commitments

This document highlights the progress and challenges in implementing international drug policy commitments, including key milestones, the mandate of the Ministerial Statement, and challenges identified during the Comprehensive Stock-taking. The discussions focus on strengthening actions at various l

0 views • 9 slides


Understanding Regulatory Requirements of Drugs and Pharmaceuticals

Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

0 views • 28 slides


Polymeric Controlled Drug Delivery Systems

Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

0 views • 33 slides


Renal Pharmacology: Drug Excretion and Renal Clearance Questions

This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

0 views • 55 slides


Understanding Nasopulmonary Drug Delivery System

Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

0 views • 35 slides


Understanding Drug Absorption Mechanisms in Pharmacy Studies

Drug absorption is a crucial process in pharmacology, involving the movement of drugs from administration sites to systemic circulation. Explore the definitions, bioavailability, routes of administration, and mechanisms like passive diffusion through cell membranes. Gain insights into how drugs disi

0 views • 13 slides


Enhancing Herbal Drug Efficacy: Novel Delivery Systems

In the modern era, herbal drugs offer a safer alternative to synthetic molecules with fewer side effects. However, their efficacy can vary due to fluctuating concentrations of active constituents. Novel Drug Delivery Systems (NDDS) such as liposomes, niosomes, and microspheres play a crucial role in

0 views • 30 slides


Understanding Physicochemical Properties of Drugs

The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

1 views • 46 slides


Understanding Formulary Systems in Healthcare

A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

0 views • 17 slides


Ways to Stay Drug Free: Lessons for Teens and Families

Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

0 views • 17 slides


Understanding the Hatch-Waxman Act: Promoting Affordable Generic Drugs

The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

0 views • 49 slides


Understanding Biopharmaceutics: pH Partition Theory and Drug Absorption

Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

0 views • 9 slides


Importance of In-Vitro Dissolution Testing in Drug Assessment

In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

10 views • 10 slides


Understanding Pharmacodynamics: Potency and Efficacy

Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

0 views • 21 slides


Understanding Drug Absorption, Excretion, and Bioavailability in Humans

Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

0 views • 24 slides


Understanding Quantitative Aspects of Drug Action

Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

0 views • 29 slides


Review of DRE School and Drug Evaluation Techniques

Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

0 views • 29 slides


Study on Juvenile Drug Crime Prevention in Taiwan: Insights from ACS Conference 2020

This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t

0 views • 20 slides


Understanding Drug Abuse: Definitions, Effects, and Stages

Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

4 views • 45 slides


Understanding Drug Targets and Mechanisms of Action

Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

3 views • 17 slides


International Day Against Drug Abuse and Illicit Trafficking 2022 Initiatives and Awareness

The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware

3 views • 9 slides


Comprehensive Review of Drugs, Categories, and Drug Influence Evaluation

This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

0 views • 28 slides


Understanding Soft Gelatin Capsules and Their Advantages

Soft gelatin capsules are one-piece forms enclosing liquid or semi-liquid fill, offering advantages such as improved bioavailability, enhanced drug stability, and easy swallowability. They come with unique features like diverse colors, sizes, and shapes. Despite their benefits, they have limitations

0 views • 28 slides


Impact of Socioeconomic Conditions on Drug Use Disorders: Insights from World Drug Report 2020

The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

0 views • 17 slides


Understanding Targeted Clinical Investigation in Pharmacovigilance

Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

0 views • 12 slides


Understanding Folate: Structure, Sources, and Bioavailability

Folate, also known as vitamin B9, plays a crucial role in various bodily functions. Folic acid and folate are different forms of the vitamin, with distinct sources and structures. Good food sources of folate include green vegetables, legumes, fruits, and fortified products. The bioavailability of fo

0 views • 24 slides


Advances in Ophthalmic Drug Delivery Systems

This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

0 views • 8 slides


State Responsible Inmates with Marijuana Convictions Research Report

Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.

0 views • 7 slides


Innovative Online Learning for Drug Court Professionals

Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

0 views • 8 slides


Understanding Drug Testing Policies in the Workplace

The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

0 views • 19 slides


Understanding Drug Metabolism: Importance and Mechanisms

Drug metabolism is a crucial process in the body that transforms drugs into forms easily excreted, affecting their efficacy and toxicity. This involves different sites such as the liver, kidney, and plasma, with enzymes in cellular organelles like cytoplasm and mitochondria playing key roles. First-

0 views • 13 slides


Understanding Azole Therapeutic Drug Monitoring for Antifungal Therapy

Azole therapeutic drug monitoring (TDM) is crucial for managing antifungal therapy due to factors like drug interactions, compliance issues, disease severity, and pharmacokinetic variability. This monitoring helps ensure optimal drug levels are maintained for effective treatment. Different TDM metho

0 views • 18 slides