Regulation of Energy Homeostasis by AMPK System and Its Modulation Factors
The AMPK system plays a crucial role in regulating energy homeostasis by sensing the cellular AMP:ATP ratio and responding to metabolic stresses that affect ATP production or consumption. AMPK is activated by factors such as hypoxia, glucose deprivation, and metabolic inhibitors, as well as by compo
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The Role of Vitamin D in Enhancing Immunity Against COVID-19
Exploring the relationship between Vitamin D and COVID-19, this research article delves into how Vitamin D mechanisms can help fight viral infections by reducing pro-inflammatory cytokines and minimizing the risk of a cytokine storm. Studies suggest that Vitamin D may play a crucial role in reducing
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Understanding Cytokines and Chemokines: Key Concepts and Implications
Cytokines and chemokines are essential signaling molecules that play crucial roles in immune responses. This content covers their general properties, classification, functions, and implications in diseases and therapies. Learn about the diverse families of cytokines, cytokine antagonists, and the va
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Understanding the Significance of Cytokines in Immune Response
Cytokines play a crucial role in immune response activation and regulation. They are secreted by various cell types like lymphocytes, monocytes, and macrophages, exerting diverse biological functions, including immune system development, inflammatory response induction, and hematopoiesis regulation.
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Role of Adhesion Molecules in Immune Response to SARS-CoV-2 Engagement
Engagement of SARS-CoV-2 triggers the complement system and TLR 7 in neutrophils and macrophages, leading to the release of inflammatory cytokines and chemotactic factors. This results in the upregulation of adhesion molecules on blood capillary endothelial cells and leukocytes, facilitating leukocy
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HerboJoint: Natural Formulation for Joint Pain Relief
Bordoloi Biotech India Pvt Ltd presents HerboJoint, a unique natural formulation designed to provide freedom from joint pain. Developed by a team of experts led by Dr. Binoy B. Bordoloi and Dr. Kulwant S. Saini, HerboJoint is a scientifically backed product combining essential oils with proven effic
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Understanding the Role of Vitamin D in Reducing COVID-19 Risk
Vitamin D plays a crucial role in reducing the risk of COVID-19 by enhancing the body's immune response, reducing production of pro-inflammatory cytokines, and increasing anti-inflammatory cytokines. Individuals at greater risk include the elderly, those with chronic diseases, dark-skinned individua
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Understanding Ankylosing Spondylitis: Causes, Symptoms, and Pathogenesis
Ankylosing spondylitis (AS) is an inflammatory disorder that primarily affects the axial skeleton. The disease causes pain, stiffness, and decreased spinal mobility, and it can lead to disability and decreased quality of life. AS is an autoimmune disease with a complex pathogenesis involving interac
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Salivary Gustin and Taste Dysfunction in Long-COVID Patients
The research explores the association between taste perception and the duration of COVID infection in long-COVID and COVID-reinfection cases. Reduced salivary gustin levels correlated with lower taste scores in long-COVID patients. The study also found an increase in the bitter taste receptor gene e
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