Computational drug discovery - PowerPoint PPT Presentation


Age-Friendly App: Managing Drug-Drug Interactions Between Prescriptions and OTC Analgesics

The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

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Master's Program in Computational Drug Discovery and Development - Fall 2024 Curriculum

This Master's program offers a comprehensive curriculum focusing on Artificial Intelligence, Computational Drug Discovery, and Development. With a blend of cutting-edge technologies and practical applications, students delve into techniques, AI/ML, big data mining, modeling, and more. Through intens

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Global Drug Discovery Outsourcing Services Market

\"The Global Drug Discovery Outsourcing Services Market Size is Anticipated to Exceed USD 7.9 Billion by 2033, Growing at a CAGR of 7.59% from 2023 to 2033.\n\"\n

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Understanding Regulatory Requirements of Drugs and Pharmaceuticals

Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

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Polymeric Controlled Drug Delivery Systems

Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

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Renal Pharmacology: Drug Excretion and Renal Clearance Questions

This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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Understanding Nasopulmonary Drug Delivery System

Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

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Understanding Physicochemical Properties of Drugs

The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

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Understanding Formulary Systems in Healthcare

A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

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Ways to Stay Drug Free: Lessons for Teens and Families

Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

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Understanding the Hatch-Waxman Act: Promoting Affordable Generic Drugs

The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

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Discovery Motions in Civil Pretrial Practice

In civil pretrial practice, discovery motions play a crucial role when the opposing party fails to respond adequately to formal discovery requests. These motions include Motion to Compel, Motion to Compel Further, and Motion to Deem Facts Admitted. By filing these motions, parties can seek court ord

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Understanding Biopharmaceutics: pH Partition Theory and Drug Absorption

Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

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Importance of In-Vitro Dissolution Testing in Drug Assessment

In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

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Considerations on 6 GHz Discovery for IEEE 802.11-18/1922r0

IEEE 802.11-18/1922r0 document discusses the background and regulatory context for supporting 6 GHz operation in 802.11ax networks. It focuses on optimizing the discovery process for 6 GHz channels to enhance STA and network KPIs. The typical scanning/discovery procedure for non-AP STAs is outlined,

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Understanding Pharmacodynamics: Potency and Efficacy

Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

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Understanding Drug Absorption, Excretion, and Bioavailability in Humans

Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

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Understanding Quantitative Aspects of Drug Action

Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

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Review of DRE School and Drug Evaluation Techniques

Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

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Study on Juvenile Drug Crime Prevention in Taiwan: Insights from ACS Conference 2020

This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t

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Understanding Drug Abuse: Definitions, Effects, and Stages

Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

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Understanding Computational Complexity Through Statistical Physics

In the age of vast data growth, tackling complex computational problems is crucial. Statistical physics can provide insights into handling the new challenges arising from the exponential increase in data. As we delve into understanding the complexity of computational tasks, it becomes evident that e

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Understanding Drug Targets and Mechanisms of Action

Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

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Data Discovery and Access Session Highlights at Carleton College

Explore the insights shared by Kristin Partlo and Danya Leebaw, Carleton College's Reference and Instruction Librarians, on the intricacies of data discovery, the marriage of discovery and analysis, mechanisms for data discovery, and specific manifestations at Carleton. Gain a deeper understanding o

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International Day Against Drug Abuse and Illicit Trafficking 2022 Initiatives and Awareness

The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware

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Service Discovery for Local Services in IEEE 11-14/0124r0 Document

Elaboration on non-tethering Soft AP and possible service network scenarios in the January 2014 IEEE document. It discusses the concept of non-tethering Soft APs, their operation in the vicinity, and the categories of use scenarios related to Internet access and service discovery. The document cover

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Comprehensive Review of Drugs, Categories, and Drug Influence Evaluation

This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

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Dynamic Bloom Filter Operation for Pre-Association Service Discovery

This document outlines a proposal for a Dynamic Bloom Filter Operation as part of a Pre-Association Service Discovery protocol to efficiently and quickly identify services offered by devices in a network. The design goals include efficiency, speed of discovery, and scalability. Challenges addressed

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Impact of Socioeconomic Conditions on Drug Use Disorders: Insights from World Drug Report 2020

The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

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Understanding Targeted Clinical Investigation in Pharmacovigilance

Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

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Pre-action Discovery in Civil Procedure: NT Supreme Court Rules

Pre-action discovery allows a party to obtain information from a potential defendant or non-party before commencing formal legal proceedings. The NT Supreme Court Rules Order 32 outline the procedures for pre-action discovery, including when there is reasonable cause to believe that relief may be ob

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Advances in Ophthalmic Drug Delivery Systems

This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

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State Responsible Inmates with Marijuana Convictions Research Report

Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.

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Innovative Online Learning for Drug Court Professionals

Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

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Understanding Drug Testing Policies in the Workplace

The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

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Exploring Computational Theories of Brain Function

In this series of images and text snippets, the discussion revolves around the emerging field of computational theories of brain function. Various aspects such as symbolic memories, the relationship between the brain and computation, the emergence of the mind from the brain, and computational thinki

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IEEE 802.11-19/2017r0 Service Discovery Advertisement

The document discusses the service discovery requirements for the IEEE 802.11bc amendment, proposing mechanisms such as beacon/periodic frame transmission, eBCS service frame request/response, and ANQP. It emphasizes the need for a broadcast discovery mechanism to cater to listening-only STAs and ou

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Cloud-Based High Performance Virtual Screening in Drug Discovery

This presentation discusses the use of cloud-based high-performance virtual screening in novel drug discovery, addressing the challenges in finding developable hit molecules and drug candidates. The case study team comprises experts from various institutions working on computational infrastructure,

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Exploring Computational Play in Early Childhood Education: DLI 2023 Workshop

The workshop at the 8th EAI International Conference on Design, Learning & Innovation (DLI 2023) in Aalborg aims to delve into the application of computational play with mathematics in early childhood education. Through live sessions and discussions, opportunities and challenges in utilizing computa

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Understanding Azole Therapeutic Drug Monitoring for Antifungal Therapy

Azole therapeutic drug monitoring (TDM) is crucial for managing antifungal therapy due to factors like drug interactions, compliance issues, disease severity, and pharmacokinetic variability. This monitoring helps ensure optimal drug levels are maintained for effective treatment. Different TDM metho

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