Understanding Cholestasis: Etiology, Clinical Manifestations, and Complications
Cholestasis is characterized by reduced bile flow and elevated direct bilirubin. It is critical to differentiate it from neonatal jaundice. In conditions like biliary atresia and 1-antitrypsin deficiency, early diagnosis and intervention are crucial to prevent liver failure. Clinical manifestations
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Evolution of Liver Biopsy in Children: ESPGHAN Position Paper
Liver biopsy plays a crucial role in diagnosing, staging, and prognostic evaluation of liver diseases in children. Indications for liver biopsy include diagnostic, prognostic, and monitoring purposes. Specific scenarios like neonatal cholestasis and progressive familial intrahepatic cholestasis requ
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