Investigating Regulation of Aging by Transcription Factors DAF-16 and SKN-1 in the IIS Pathway in C. elegans
Aging regulation in eukaryotic organisms, particularly in Caenorhabditis elegans, is studied through the Insulin/Insulin-like Growth Factor-1 Signaling pathway. This research focuses on understanding how transcription factors DAF-16 and SKN-1 may act together to promote longevity by reducing the IIS
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Research Update: Sofie's Lab Book Journey from October 2018 to December 2019
Sofie's research progress includes training on C. elegans and drosophila, meetings with various groups, preparing for conferences, and application for funding. She is focused on stem cell research, premature aging studies, and biomarker analysis in CSF.
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Regulation of Aging by Transcription Factors DAF-16 and SKN-1 in the IIS Pathway
Investigating how transcription factors DAF-16 and SKN-1 regulate aging in the IIS pathway of C. elegans can provide valuable insights into longevity and stress resistance. This study explores the molecular mechanisms involved in promoting longevity and controlling gene expression during the down-re
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Investigating the Role of Amino Acid 381 in BK Channel Clustering
The study explores the significance of amino acid 381 in the function of dystrophin to localize SLO-1 in C. elegans. By utilizing the T381I mutation, the research aims to determine whether a SLO-1 BK channel with this mutation exhibits a clustered or non-clustered phenotype. Proposed methods involve
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