Cholestatic liver disease affects Alkaline Phosphatase (ALP) and bilirubin levels, indicating bile duct damage. GGT and 5'-Nucleotidase help differentiate hepatobiliary vs. bone origin of ALP elevation. ALP is produced by bile duct epithelium and can be normal in acute biliary obstruction. GGT and N

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Exploring the hepatobiliary system through radiology, this lecture covers the anatomy, modalities like X-ray, Ultrasound, CT scan, MRI, and nuclear scan used for imaging, their advantages, disadvantages, and indications. It delves into the significance of liver, gallbladder, and biliary duct imaging

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Cholestasis is characterized by reduced bile flow and elevated direct bilirubin. It is critical to differentiate it from neonatal jaundice. In conditions like biliary atresia and 1-antitrypsin deficiency, early diagnosis and intervention are crucial to prevent liver failure. Clinical manifestations

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Superior Vena Cava (SVC) occlusion secondary to postradiation fibrosis is a rare condition that can lead to debilitating symptoms. In this case study, a 47-year-old male with a history of Hodgkin lymphoma treated with chest radiotherapy presented with exertional chest pain and other associated sympt

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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Choledochal cysts are congenital anomalies of the biliary tract characterized by cystic dilatation at various segments. They can lead to complications like biliary cirrhosis and recurrent pancreatitis. Clinical features include jaundice, abdominal pain, and right epigastric mass. Early detection is

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Liver biopsy plays a crucial role in diagnosing, staging, and prognostic evaluation of liver diseases in children. Indications for liver biopsy include diagnostic, prognostic, and monitoring purposes. Specific scenarios like neonatal cholestasis and progressive familial intrahepatic cholestasis requ

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This informative content delves into the anatomy and function of the gallbladder, discussing its role in storing and concentrating bile. It explains the composition of bile, the process of emulsifying fats, and the consequences of bile flow obstruction. Various disorders affecting the biliary system

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Native RVOT stenting in TOF+PS patients can be challenging due to anatomical complexities like short infundibulum and VSD. Different equipment and techniques are used for crossing tricuspid and pulmonary valves and delivering the stent. Dilating the pulmonary valve and addressing residual stenosis a

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Photosensitization in plants can lead to abnormal skin sensitivity to sunlight, caused by the presence of photodynamic agents in the skin and peripheral circulation. Primary and secondary photosensitization are common, with various plants and toxins contributing to liver damage and biliary occlusion

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Ascites, jaundice, and confusion in a 50-year-old man raise concerns about liver disease. Differential diagnosis includes cirrhosis, malignancy, alcoholic liver disease, and biliary obstruction. Physical examination findings such as spider naevi, hepatomegaly, and asterixis help narrow down the poss

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This presentation covers the diagnostic approach and management strategies for dysphagia in a 65-year-old patient presenting with symptoms such as odynophagia, cough, hoarseness, and lymphadenopathy. It discusses the use of CBC, CXR, ECG, upper GI endoscopy, CT, and biopsy in assessing the location,

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Collaborative meta-analysis explores the efficacy of long-term dual antiplatelet therapy in preventing cardiovascular events in patients with previous myocardial infarction. Trials show heterogeneous results on the benefits and safety of prolonged therapy, with varying recommendations based on patie

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In this informative presentation by Assistant Professor Dr. Emre Hamurtekin, the focus is on gastrointestinal secretions including salivary, gastric, pancreatic, biliary, and intestinal fluids. Structural considerations such as the surface area for absorption, sphincters, villi, and crypts are discu

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Hepatobiliary and pancreatic disorders can lead to conditions like jaundice, caused by an accumulation of bilirubin. Jaundice can be classified as prehepatic, intrahepatic, or posthepatic depending on the underlying causes such as liver damage, hepatitis, cirrhosis, or bile duct obstructions. Liver

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Recent clinical trials such as TOPAZ-1, KEYNOTE-966, ClarIDHy, and FIGHT-202 have shown promising results in the treatment of cholangiocarcinoma. Trials with immunotherapy and targeted therapy have demonstrated improved overall survival rates, progression-free survival, and objective response rates

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In the realm of pharmacology, the process of eliminating drugs from the body involves hepatic metabolism, biliary elimination, and urinary excretion. Once a drug is introduced into the system, these routes of elimination come into play, highlighting the crucial role they play in drug clearance and e

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Explore the anatomy of the biliary tract, including pathways of cholesterol metabolism in the liver and the composition of bile. Learn about conditions such as gallstones, polyps, and common bile duct abnormalities, as well as diagnostic procedures like ERCP. Discover indications for biliary stentin

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Explore the surgical procedure of cholecystectomy, involving the complete removal of the gallbladder, and learn about the anatomy and function of the biliary system. Discover common pathologies like cholecystitis and cholelithiasis, as well as the types of gallstones. Visual aids and detailed explan

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