Enhancing Biological Context Annotation for AOPs: A Comprehensive Approach
Manual creation and homogenization of biological context annotations for AOPs and key events help in interlinking different AOPs to understand possible connections between pathways. The process involves compiling AOPs for various organisms, including humans and model species, annotating key events w
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Understanding Skin Sensitisation through Adverse Outcome Pathways (AOP)
The Adverse Outcome Pathway (AOP) for Skin Sensitisation provides a mechanistic framework linking Molecular Initiating Events (MIE) to Adverse Outcomes (AO) through Key Events (KE) and Key Event Relationships (KER). AOPs offer a transparent justification for toxicological predictions and play a vita
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