Explore Zilebesiran, an investigational RNA interference therapeutic targeting hepatic AGT synthesis for hypertension. Primary findings from Phase 2 trial KARDIA-1 reveal sustained blood pressure reduction. Addressing the unmet need for innovative antihypertensive treatments.

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Explore the classification of antihypertensive agents used in treating hypertension, including beta blockers, centrally acting agents, ganglionic blockers, ACE inhibitors, vasodilators, and more. Learn about the Renin-Angiotensin System, ACE inhibitors, and specific drugs like Captopril and Benazepr

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In the management of acute ischemic stroke, the primary goals are to reduce secondary brain damage, maintain adequate perfusion, and prevent recurrent strokes by managing risk factors. Treatment includes maintaining tissue oxygenation, correcting volume status and electrolytes, managing blood glucos

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A 38-year-old female with a history of resistant hypertension and hypokalemia was referred for evaluation. She had been on multiple antihypertensive medications but still had uncontrolled blood pressure and low potassium levels. After treatment with potassium supplementation and adjustment of medica

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High blood pressure (BP) is considered a trait rather than a specific disease, with risks increasing with age. Antihypertensive therapy has shown to reduce the incidence of stroke and coronary artery disease. Managing hypertension effectively involves a holistic approach targeting modifiable risk fa

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Expert recommendations for the management of covert cerebral small vessel disease (ccSVD) emphasize the use of antihypertensive treatment for hypertensive patients to prevent SVD lesion progression. While there is limited evidence supporting intensive blood pressure lowering targets, systematic bloo

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Explore the world of cardiovascular drugs, including antihypertensive, antianginal, heart failure, antiarrhythmic, diuretic, antithrombotic, and antihyperlipidemic medications. Dive into the mechanisms of action, clinical indications, and adverse effects of these drugs, gaining valuable insights int

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Hypertension, characterized by high blood pressure, can lead to serious health issues if left untreated. Essential hypertension is common, with various risk factors such as family history and lifestyle choices contributing to its development. Antihypertensive drugs play a crucial role in managing bl

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Chronic hypertension in pregnancy, sometimes complicated by preeclampsia, poses risks to both mother and baby. The prevalence is increasing, linked to factors like obesity and delayed childbearing. Diagnosis can be challenging due to normal pregnancy physiology masking underlying hypertension. Guide

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