Explore Zilebesiran, an investigational RNA interference therapeutic targeting hepatic AGT synthesis for hypertension. Primary findings from Phase 2 trial KARDIA-1 reveal sustained blood pressure reduction. Addressing the unmet need for innovative antihypertensive treatments.

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Join us at our MarketsandMarkets 5th Annual Orphan Drugs and Rare Diseases Conference in Germany, Europe, for a groundbreaking exploration of the recent advances in developing life-saving therapies, technologies in diagnosing, and strategies to enhance orphan drug development.\n\nEnquire Now @ https

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Antiarrhythmic drugs are classified into different classes based on their mechanisms of action. Class I includes sodium channel blockers with specific drugs like procainamide, disopyramide, and quinidine. Class 1B involves lidocaine and mexiletine. Class 1C consists of agents like flecainide. Class

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Antipsychotic drugs, also known as neuroleptics, are essential in treating schizophrenia and other psychotic disorders. They work by targeting dopamine and serotonin receptors in the brain, managing symptoms like hallucinations and delusions. Learn about the dopamine-serotonin hypothesis of schizoph

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Providing guidance on types of Expanded Access for drugs, biologics, and devices, this content explains the concept of Expanded Access and the criteria that must be met. It covers different types of Expanded Access for drugs and devices, emphasizing the importance of patient safety and benefit. The

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Join us at our MarketsandMarkets Orphan Drugs and Rare Diseases Conference in Boston, USA for a groundbreaking exploration of the recent advances in developing life-saving therapies, technologies in diagnosing, and strategies to enhance orphan drug development.\n\nRegister Now @ \/\/events.marketsan

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Learn about the hazards of exposure to hazardous drugs, including potential health risks such as cancer, nausea, reproductive toxicity, and organ damage. Explore training modules, drug categories, and a list of hazardous drugs to ensure workplace safety. Discover NIOSH criteria for identifying hazar

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The Drugs and Cosmetics Act of 1940 was enacted to regulate the import, manufacture, distribution, and sale of drugs and cosmetics in India. The Act aims to ensure high standards of medical treatment, prevent substandard drugs, and establish advisory boards for different types of drugs. It sets out

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Crude drugs are natural substances obtained from plants, animals, and minerals. They are used without much processing and have therapeutic properties. Different plant parts like leaves, flowers, fruits, seeds, roots, bark, and stems yield various important drugs. Animals and minerals also serve as s

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Drugs can be sourced from six major categories: plants, animals, minerals/earth, microbiological sources, semi-synthetic sources, synthetic sources, and recombinant DNA technology. Plant sources, being the oldest, provide various medicinal properties through leaves, flowers, fruits, seeds, roots, ba

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The Drugs and Magic Remedies (Objectionable Advertisements) Act of 1954 regulates the advertising of drugs and remedies claiming magical properties in India. It defines drugs and magic remedies, prohibits certain types of advertisements related to drugs, and aims to control misleading marketing prac

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The Drugs and Cosmetics Act of 1940 and its Rules of 1945 were established to regulate the import, manufacture, distribution, and sale of drugs and cosmetics in India. The Act ensures that only qualified individuals are involved in these processes and aims to prevent the entry of substandard or spur

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Explore the classification of antihypertensive agents used in treating hypertension, including beta blockers, centrally acting agents, ganglionic blockers, ACE inhibitors, vasodilators, and more. Learn about the Renin-Angiotensin System, ACE inhibitors, and specific drugs like Captopril and Benazepr

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Anxiety disorders are conditions characterized by excessive worry and fear that can interfere with daily life. Common types include generalized anxiety disorder, panic disorder, phobias, and OCD. Treatment options include psychotherapy and anxiolytic drugs such as benzodiazepines, 5HT1A agonists, be

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Anticestodal drugs play a crucial role in combating tapeworm infections in veterinary medicine. These drugs are classified into taeniafuges and taenicides, with examples of natural and synthetic compounds highlighted. Natural compounds like pumpkin seeds and male fern are traditionally used for thei

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The Central Drug Standard Control Organisation (CDSCO) is the main regulatory body in India for pharmaceuticals, medical devices, and clinical trials. It functions under the Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India. The CDSCO is responsible f

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Generic drugs are identical copies of brand-name medications in dosage, strength, quality, and intended use. They contain the same active ingredients but are sold under their chemical name. This article explores the basic differences between generic and brand-name drugs, when generic drugs are marke

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Tuberculosis is a chronic granulomatous disease caused by Mycobacterium bovis in ruminants and Mycobacterium avium in dogs and pigs. These bacteria have a unique waxy appearance due to their cell wall composition, providing a shield against pharmacological compounds. Antitubercular drugs play a cruc

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Renal block plays a crucial role in drug excretion, with processes like glomerular filtration and tubular secretion affecting drug elimination. Factors like blood flow, physiochemical properties, and urine pH influence renal excretion of drugs. Competition between drugs for transporters can have ben

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The development of antimicrobial drugs has significantly improved therapeutics by controlling infections and preventing complications. These drugs target invading microorganisms using selective toxicity, sparing host cells. Antimicrobial drugs are classified based on site, mechanism of action, and c

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The Central Nervous System (CNS) plays a crucial role in coordinating the body's functions and responses to the environment. Drugs acting on the CNS can be classified into CNS stimulants and CNS depressants. CNS stimulants include spinal, medullary, and cortical stimulants, with various direct and i

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Protozoal infections are widespread, impacting both developed and underdeveloped regions due to globalization. Antiprotozoal drugs are crucial for treating diseases like malaria, amebiasis, and more. However, these drugs can have potent toxic effects on host cells. This article delves into the class

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In the management of acute ischemic stroke, the primary goals are to reduce secondary brain damage, maintain adequate perfusion, and prevent recurrent strokes by managing risk factors. Treatment includes maintaining tissue oxygenation, correcting volume status and electrolytes, managing blood glucos

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Understanding the mechanism of ovulation and hormonal regulation is key in classifying drugs used to induce ovulation. This lecture covers the pharmacology of different groups of drugs, their mechanisms of action, administration protocols, indications, efficacy rates, and adverse effects. Antiestrog

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The DAVA Drugs Authentication & Verification Application, developed by the National Informatics Centre of the Government of India, enables authentication, tracking, and tracing of Indian drugs at different packaging levels. Manufacturers maintain Unique Serial Numbers for primary and secondary packa

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This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

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Pharmacognosy is the study of medicines derived from natural sources, exploring drugs from plants through the lenses of botany, chemistry, and pharmacology. This includes the classification of vegetable drugs based on taxonomic, chemical, and morphological characteristics. Understanding key points f

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A 38-year-old female with a history of resistant hypertension and hypokalemia was referred for evaluation. She had been on multiple antihypertensive medications but still had uncontrolled blood pressure and low potassium levels. After treatment with potassium supplementation and adjustment of medica

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High blood pressure (BP) is considered a trait rather than a specific disease, with risks increasing with age. Antihypertensive therapy has shown to reduce the incidence of stroke and coronary artery disease. Managing hypertension effectively involves a holistic approach targeting modifiable risk fa

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This lecture covers factors influencing placental transfer, harmful effects of drugs at different developmental stages, FDA classifications of drugs, and teratogenic drugs. It explains how drugs cross the placenta, including physiochemical properties and stage of development affecting transfer. The

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Expert recommendations for the management of covert cerebral small vessel disease (ccSVD) emphasize the use of antihypertensive treatment for hypertensive patients to prevent SVD lesion progression. While there is limited evidence supporting intensive blood pressure lowering targets, systematic bloo

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Explore the world of cardiovascular drugs, including antihypertensive, antianginal, heart failure, antiarrhythmic, diuretic, antithrombotic, and antihyperlipidemic medications. Dive into the mechanisms of action, clinical indications, and adverse effects of these drugs, gaining valuable insights int

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Understanding the classes of drugs used to control or prevent vertigo, identifying disorders of balance, and detailing drugs used for vertigo management. Learn about drugs that can trigger vertigo and the mind map of specific treatments involving various medications.

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Hypertension, characterized by high blood pressure, can lead to serious health issues if left untreated. Essential hypertension is common, with various risk factors such as family history and lifestyle choices contributing to its development. Antihypertensive drugs play a crucial role in managing bl

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Chronic hypertension in pregnancy, sometimes complicated by preeclampsia, poses risks to both mother and baby. The prevalence is increasing, linked to factors like obesity and delayed childbearing. Diagnosis can be challenging due to normal pregnancy physiology masking underlying hypertension. Guide

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This session delves into the world of drugs, highlighting the characteristics and effects of substances like cannabis, heroin, LSD, ecstasy, cocaine, and NPS. Participants engage in activities matching drug descriptions with names, followed by developing presentations on the drugs. Discussions inclu

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The Drugs and Magic Remedies Act 1954 regulates the advertisement of drugs and prohibits the promotion of remedies claiming magical qualities. It defines various terms related to drugs and advertisements, while emphasizing the need for ethical and truthful advertising to protect the public. The Act

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Pharmacognosy is the study of medicinal drugs derived from natural sources, focusing on the properties and origins of crude drugs like plants and animals. The term was coined in 1815, emphasizing knowledge of drugs' physical, chemical, and biological properties. It is associated with various branche

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Date rape drugs, often referred to as club drugs, are commonly used at dance clubs, concerts, raves, and parties. Rohypnol, also known as Roofies, is a depressant drug prescribed in Europe for sleep and pre-surgery relaxation. It is orally taken in various colored pills, such as olive green or white

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Streptomycin, isoniazid, rifampin, and other anti-TB drugs are crucial in treating tuberculosis. Learn about first-line, second-line, and newer drugs, along with combination therapy. Explore the mechanisms and clinical applications of these drugs in combating TB infections.

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