Insights into Antibacterials: Mechanisms and Resistance
Antibiotics play a crucial role in combating microbial infections, but the emergence of antimicrobial resistance poses a significant challenge. Understanding the mechanisms by which antibacterial agents work, such as inhibiting cell wall synthesis, disrupting protein synthesis, and inhibiting metabo
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Understanding Antibiotics: Types, Mechanisms, and Usage
Antibiotics, or antibacterials, are essential antimicrobial drugs used to treat and prevent bacterial infections. They work by either killing or inhibiting the growth of bacteria. They are classified based on factors like mechanism of action, chemical structure, and spectrum of activity. Factors inf
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Analysis of Antibacterials Commercial Launches and Patient Access Trends
The study examines the commercial launch and patient access of new antibacterials approved in the last decade. Results show challenges in timely launches across countries, with limited commercial success despite regulatory approvals. The impact of sponsor characteristics, drug resistance, and WHO li
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Challenges in Discovering Novel Antibacterials
Lynn L. Silver, Ph.D., discusses the difficulties in discovering new antibacterials, highlighting the limited success in bringing novel classes to the clinic in recent years. The timeline and strategies for antibacterial discovery by Big Pharma are explored, along with potential solutions to overcom
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