Understanding Hypothalamus and Pituitary Hormones in Clinical Pharmacology
Peptides and glycoproteins are secreted by the hypothalamus and pituitary, regulating anterior pituitary hormones. Hormones like adrenocorticotropic hormone (ACTH) and corticotropin-releasing hormone (CRH) play crucial roles. Synthetic adrenocorticosteroids have limited the use of corticotropin for
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Understanding Hormones and their Role in the Body
Hormones are chemical messengers that play a crucial role in regulating various metabolic functions in the body. They are transported through the bloodstream to tissues and organs, affecting processes like growth, metabolism, and reproduction. Some hormones have autocrine and paracrine effects in ad
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Pituitary Incidentaloma: Evaluation and Management Recommendations
A pituitary incidentaloma is an unsuspected pituitary lesion discovered incidentally during imaging studies not done for lesion-related symptoms. Patients should undergo a thorough evaluation for hormone hypersecretion and hypopituitarism, including clinical and laboratory assessments. Recommendatio
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Understanding the Pituitary Gland: Structure, Function, and Hormones
The pituitary gland, located at the base of the brain, comprises two main portions - the anterior lobe (adenohypophysis) and the neurohypophysis. The anterior lobe consists of various cell types that secrete hormones like GH, prolactin, TSH, ACTH, FSH, and LH. GH, also known as STH, plays a crucial
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Comprehensive Case Study: Management of Hypercortisolism in a Patient with Cushing's Disease
A 34-year-old married woman with Cushing's Disease and hypercortisolism presented with various symptoms including galactorrhea, weight gain, hirsutism, acne, and dysglycemia. Following transsphenoidal surgery (TSS), she experienced clinical and biochemical recovery, with improvements in weight, hirs
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