Genomic Selection in Dairy Cattle: Advantages, Disadvantages, and Impact

Genomic selection in dairy cattle focuses on specialized breeds like Holstein, Jersey, Brown Swiss, and Ayrshire. It brings reliable breeding values at a young age, higher success rates in obtaining top bulls, and lower costs for test proofs, leading to a shorter generation interval. While it offers advantages such as increased genetic improvement and wider portfolios of commercial bulls, there are drawbacks, including the need for a large set of genotyped animals and high genotyping costs.

• Genomic Selection
• Dairy Cattle
• Breeding Values
• Genetic Improvement
• Holstein

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1. Genomic Selection in Dairy Cattle Dr.Wuttigrai Boonkum

2. Genomic Selection Dairy cattle most are specialised dairy breed Holstein, Jersey, Brown Swiss, Ayrshire Some dual propose Simmental, Montbeliarde, Normande, etc More than 80% AI from AI companies Global exchange of genetic so international genetic evaluation

3. Genomic Selection P = G + E Genetic evaluation or Molecular genetics Appropriated major gene only Need time and data complete

4. Genomic Selection, What does it bring us? Reliable breeding values at young age higher success rate to get top bulls lower costs for test proofs shorter generation-interval

5. Reliability of breeding values Categorie Parent average GS young bull 1st EBV (prog.) 2nd EBV (prog.) 89% Production Type 35% 50-55% 80% Longevity 30% 40-45% 50-65% 50-80% 35% 45-50% 75% 81% 50% reliability is realistic

6. Advantages of Genomic Selection Increased genetic improvement (30-40%) Higher genetic level of test sires Higher genetic level of Delta embryo s Wider portfolio of commercial bulls & higher level More outcross; less inbreeding

7. Disadvantages of Genomic Selection New method, not fully proven or tested Need to genotype a sufficiently large set of animals for accurate GEBV Across breed accuracy low Genotypes still costly (10,000 bath/head)

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10. TMZ TF Friebrah

11. 3. Table 3Comparison of average of milk yield, reproductive performance and economic returns of Thai Friesian (TF), Thai milking zebu (TMZ) and Friebrah (FB) Dairy cattle crossbreds Traits TF TMZ FB Milk yield (kg/head/lactation) Milk yield (kg/head/day) Day in milk(day) First oestrus after calving(day) Calving interval(day) Number of service per conception(times) Income(baht/lactation) Production cost(baht/lactation) Milk production cost(baht/kg) Net profit(baht) 4,517.76+384.19 14.39+2.92 314.45+24 69.17+28 415.10+72 2.10+0.87 52,406.01 29,795.39 3,902.57+460.91 13.34+4.06 292.30+28 68.19+43 399.90+49 1.70+0.82 45,269.87 28,032.08 2,472.90+456.12 9.20+1.21 268.50+51 54.23+28 363.70+43 1.40+0.69 28,676.24 24,646.17 6.37 7.49 9.91 22,610.62 17,237.79 4,030.07 Source:( , 2549 , )

12. 4. Heritability high medium, low BLUP BLUP Traditional Selection index by MT-BLUP G MAS Selection index by MA-BLUP G G Selection index including MA information Pre-selection by marker confirmed by MT-BLUP index G Figure 6 Dairy cattle improvement using BLUP and genetic marker scheme